Identity
HGNC
LOCATION
1p36.12
LOCUSID
ALIAS
ACAP4,CENTB6,DDEFL1,UPLC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55616
MIM: 616594
HGNC: 14987
Ensembl: ENSG00000088280
Variants:
dbSNP: 55616
ClinVar: 55616
TCGA: ENSG00000088280
COSMIC: ASAP3
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Endocytosis | KEGG | ko04144 |
| Endocytosis | KEGG | hsa04144 |
| Fc gamma R-mediated phagocytosis | KEGG | ko04666 |
| Fc gamma R-mediated phagocytosis | KEGG | hsa04666 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30536996 | 2019 | MicroRNA-143-3p inhibits colorectal cancer metastases by targeting ITGA6 and ASAP3. | 36 |
| 31182282 | 2019 | ACAP4 interacts with CrkII to promote the recycling of integrin β1. | 2 |
| 30536996 | 2019 | MicroRNA-143-3p inhibits colorectal cancer metastases by targeting ITGA6 and ASAP3. | 36 |
| 31182282 | 2019 | ACAP4 interacts with CrkII to promote the recycling of integrin β1. | 2 |
| 30395269 | 2018 | Acetylation of ACAP4 regulates CCL18-elicited breast cancer cell migration and invasion. | 17 |
| 30395269 | 2018 | Acetylation of ACAP4 regulates CCL18-elicited breast cancer cell migration and invasion. | 17 |
| 28502111 | 2017 | Upregulation of ASAP3 contributes to colorectal carcinogenesis and indicates poor survival outcome. | 6 |
| 28502111 | 2017 | Upregulation of ASAP3 contributes to colorectal carcinogenesis and indicates poor survival outcome. | 6 |
| 24078447 | 2014 | ASAP3 expression in non-small cell lung cancer: association with cancer development and patients' clinical outcome. | 11 |
| 24284654 | 2014 | Loss of ASAP3 destabilizes cytoskeletal protein ACTG1 to suppress cancer cell migration. | 17 |
| 24078447 | 2014 | ASAP3 expression in non-small cell lung cancer: association with cancer development and patients' clinical outcome. | 11 |
| 24284654 | 2014 | Loss of ASAP3 destabilizes cytoskeletal protein ACTG1 to suppress cancer cell migration. | 17 |
| 23776207 | 2013 | Phosphorylation of the Bin, Amphiphysin, and RSV161/167 (BAR) domain of ACAP4 regulates membrane tubulation. | 11 |
| 23776207 | 2013 | Phosphorylation of the Bin, Amphiphysin, and RSV161/167 (BAR) domain of ACAP4 regulates membrane tubulation. | 11 |
| 22027826 | 2011 | ACAP4 protein cooperates with Grb2 protein to orchestrate epidermal growth factor-stimulated integrin β1 recycling in cell migration. | 12 |
Citation
Dessen P
ASAP3 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 3)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42769/asap3
