Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7410
MIM: 600428
HGNC: 12658
Ensembl: ENSG00000160293
Variants:
dbSNP: 7410
ClinVar: 7410
TCGA: ENSG00000160293
COSMIC: VAV2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000160293 | ENST00000371850 | P52735 |
| ENSG00000160293 | ENST00000371851 | P52735 |
| ENSG00000160293 | ENST00000406606 | P52735 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38374399 | 2024 | VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma. | 1 |
| 38374399 | 2024 | VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma. | 1 |
| 36631800 | 2023 | AFAP1L1 promotes gastric cancer progression by interacting with VAV2 to facilitate CDC42-mediated activation of ITGA5 signaling pathway. | 3 |
| 37804474 | 2023 | Vav2 promotes ductus arteriosus anatomic closure via the remodeling of smooth muscle cells by Rac1 activation. | 0 |
| 36631800 | 2023 | AFAP1L1 promotes gastric cancer progression by interacting with VAV2 to facilitate CDC42-mediated activation of ITGA5 signaling pathway. | 3 |
| 37804474 | 2023 | Vav2 promotes ductus arteriosus anatomic closure via the remodeling of smooth muscle cells by Rac1 activation. | 0 |
| 36039727 | 2022 | Potentially functional genetic variants of VAV2 and PSMA4 in the immune-activation pathway and non-small cell lung cancer survival. | 2 |
| 36426134 | 2022 | The tRNA-Cys-GCA Derived tsRNAs Suppress Tumor Progression of Gliomas via Regulating VAV2. | 7 |
| 36039727 | 2022 | Potentially functional genetic variants of VAV2 and PSMA4 in the immune-activation pathway and non-small cell lung cancer survival. | 2 |
| 36426134 | 2022 | The tRNA-Cys-GCA Derived tsRNAs Suppress Tumor Progression of Gliomas via Regulating VAV2. | 7 |
| 34462423 | 2021 | VAV2 is required for DNA repair and implicated in cancer radiotherapy resistance. | 10 |
| 34462423 | 2021 | VAV2 is required for DNA repair and implicated in cancer radiotherapy resistance. | 10 |
| 32495883 | 2020 | SNHG3 silencing suppresses the malignant development of triple-negative breast cancer cells by regulating miRNA-326/integrin α5 axis and inactivating Vav2/Rac1 signaling pathway. | 11 |
| 32897354 | 2020 | Biochemical and NMR characterization of the interactions of Vav2-SH2 domain with lipids and the EphA2 juxtamembrane region on membrane. | 4 |
| 32963234 | 2020 | VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma. | 24 |
Citation
Dessen P
VAV2 (vav guanine nucleotide exchange factor 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42781/vav2
