VCAM1 (vascular cell adhesion molecule 1)

2003-06-01  

Identity

HGNC
LOCATION
1p21.2
LOCUSID
ALIAS
CD106,INCAM-100
FUSION GENES

Other Information

Locus ID:

NCBI: 7412
MIM: 192225
HGNC: 12663
Ensembl: ENSG00000162692

Variants:

dbSNP: 7412
ClinVar: 7412
TCGA: ENSG00000162692
COSMIC: VCAM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162692ENST00000294728P19320
ENSG00000162692ENST00000347652P19320
ENSG00000162692ENST00000370115E9PDD2
ENSG00000162692ENST00000370119P19320
ENSG00000162692ENST00000650339A0A3B3ISS8

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Leukocyte transendothelial migrationKEGGko04670
Cell adhesion molecules (CAMs)KEGGhsa04514
Leukocyte transendothelial migrationKEGGhsa04670
MalariaKEGGko05144
MalariaKEGGhsa05144
African trypanosomiasisKEGGko05143
African trypanosomiasisKEGGhsa05143
HTLV-I infectionKEGGko05166
HTLV-I infectionKEGGhsa05166
NF-kappa B signaling pathwayKEGGhsa04064
NF-kappa B signaling pathwayKEGGko04064
TNF signaling pathwayKEGGhsa04668
TNF signaling pathwayKEGGko04668
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon gamma signalingREACTOMER-HSA-877300
Signaling by InterleukinsREACTOMER-HSA-449147
Extracellular matrix organizationREACTOMER-HSA-1474244
Integrin cell surface interactionsREACTOMER-HSA-216083
AGE-RAGE signaling pathway in diabetic complicationsKEGGko04933
AGE-RAGE signaling pathway in diabetic complicationsKEGGhsa04933
Interleukin-4 and 13 signalingREACTOMER-HSA-6785807
Fluid shear stress and atherosclerosisKEGGko05418
Fluid shear stress and atherosclerosisKEGGhsa05418

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380654812024Elevated VCAM-1 levels in peripheral blood are associated with brain structural and functional alterations in major depressive disorder.0
384912162024Endothelial cell-derived extracellular vesicles expressing surface VCAM1 promote sepsis-related acute lung injury by targeting and reprogramming monocytes.3
384974802024Associations of Circulating Vascular Cell Adhesion Molecule-1 and Intercellular Adhesion Molecule-1 With Long-Term Cardiac Function.1
384987012024Interactions between integrin α9β1 and VCAM-1 promote neutrophil hyperactivation and mediate poststroke DVT.0
387105942024Increased Expression of VCAM1 on Brain Endothelial Cells Drives Blood-Brain Barrier Impairment Following Chronic Cerebral Hypoperfusion.0
380654812024Elevated VCAM-1 levels in peripheral blood are associated with brain structural and functional alterations in major depressive disorder.0
384912162024Endothelial cell-derived extracellular vesicles expressing surface VCAM1 promote sepsis-related acute lung injury by targeting and reprogramming monocytes.3
384974802024Associations of Circulating Vascular Cell Adhesion Molecule-1 and Intercellular Adhesion Molecule-1 With Long-Term Cardiac Function.1
384987012024Interactions between integrin α9β1 and VCAM-1 promote neutrophil hyperactivation and mediate poststroke DVT.0
387105942024Increased Expression of VCAM1 on Brain Endothelial Cells Drives Blood-Brain Barrier Impairment Following Chronic Cerebral Hypoperfusion.0
357784872023EPSTI1 promotes monocyte adhesion to endothelial cells in vitro via upregulating VCAM-1 and ICAM-1 expression.2
361952452023VCAM-1 and GFPT-2: Predictive markers of osteoblast differentiation in human dental pulp stem cells.3
365259052023The role of VCAM-1 in diabetic retinopathy: A systematic review and meta-analysis.2
372286102023Human IL-32θA94V mutant attenuates monocyte-endothelial adhesion by suppressing the expression of ICAM-1 and VCAM-1 via binding to cell surface receptor integrin αVβ3 and αVβ6 in TNF-α-stimulated HUVECs.3
357784872023EPSTI1 promotes monocyte adhesion to endothelial cells in vitro via upregulating VCAM-1 and ICAM-1 expression.2

Citation

Dessen P

VCAM1 (vascular cell adhesion molecule 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42784/favicon/tumors-explorer/js/web-card-gene.js