LYVE1 (lymphatic vessel endothelial hyaluronan receptor 1)

2003-05-01  

Identity

HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
CRSBP-1,HAR,LYVE-1,XLKD1

Other Information

Locus ID:

NCBI: 10894
MIM: 605702
HGNC: 14687
Ensembl: ENSG00000133800

Variants:

dbSNP: 10894
ClinVar: 10894
TCGA: ENSG00000133800
COSMIC: LYVE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133800ENST00000256178Q9Y5Y7
ENSG00000133800ENST00000256178B2R672
ENSG00000133800ENST00000438354E7EPC7
ENSG00000133800ENST00000529598F2Z296

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Hyaluronan metabolismREACTOMER-HSA-2142845
Hyaluronan uptake and degradationREACTOMER-HSA-2160916

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
378101972023hsa_circ_0129047 Upregulates LYVE1 to Inhibit Hepatocellular Carcinoma Progression by Sponging miR-492.2
378101972023hsa_circ_0129047 Upregulates LYVE1 to Inhibit Hepatocellular Carcinoma Progression by Sponging miR-492.2
347756722022The prognostic influence of lymphatic endothelium-specific hyaluronan receptor 1 in cancer: A systematic review.8
351592212022Single-Cell RNA-Seq Reveals a Crosstalk between Hyaluronan Receptor LYVE-1-Expressing Macrophages and Vascular Smooth Muscle Cells.9
347756722022The prognostic influence of lymphatic endothelium-specific hyaluronan receptor 1 in cancer: A systematic review.8
351592212022Single-Cell RNA-Seq Reveals a Crosstalk between Hyaluronan Receptor LYVE-1-Expressing Macrophages and Vascular Smooth Muscle Cells.9
334465032021An immunohistochemical study of lymphatic elements in the human brain.30
334465032021An immunohistochemical study of lymphatic elements in the human brain.30
312501322020Elevated lymphatic vessel density measured by Lyve-1 expression in areas of replacement fibrosis in the ventricular septum of patients with hypertrophic obstructive cardiomyopathy (HOCM).4
312501322020Elevated lymphatic vessel density measured by Lyve-1 expression in areas of replacement fibrosis in the ventricular septum of patients with hypertrophic obstructive cardiomyopathy (HOCM).4
294256952019Hyaluronan in the lymphatics: The key role of the hyaluronan receptor LYVE-1 in leucocyte trafficking.58
306552862019Long noncoding RNA ANRIL regulates endothelial cell activities associated with coronary artery disease by up-regulating CLIP1, EZR, and LYVE1 genes.31
312277952019Hyaluronan and LYVE-1 and allograft function in lung transplantation recipients.4
313462342019Serum sLYVE-1 is not associated with coronary disease but with renal dysfunction: a retrospective study.0
294256952019Hyaluronan in the lymphatics: The key role of the hyaluronan receptor LYVE-1 in leucocyte trafficking.58

Citation

Dessen P

LYVE1 (lymphatic vessel endothelial hyaluronan receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42844/lyve1