YY1AP1 (YY1 associated protein 1)

2003-06-01  

Identity

HGNC
YY1AP1
LOCATION
1q22
LOCUSID
55249
ALIAS
GRNG,HCCA1,HCCA2,YY1AP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55249
MIM: 607860
HGNC: 30935
Ensembl: ENSG00000163374

Variants:

dbSNP: 55249
ClinVar: 55249
TCGA: ENSG00000163374
COSMIC: YY1AP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163374ENST00000295566Q9H869
ENSG00000163374ENST00000311573Q9H869
ENSG00000163374ENST00000347088Q9H869
ENSG00000163374ENST00000354691B4DZQ4
ENSG00000163374ENST00000355499Q9H869
ENSG00000163374ENST00000359205Q9H869
ENSG00000163374ENST00000361140Q68CT8
ENSG00000163374ENST00000361831Q9H869
ENSG00000163374ENST00000368330Q9H869
ENSG00000163374ENST00000368339Q9H869
ENSG00000163374ENST00000368340Q9H869
ENSG00000163374ENST00000404643Q9H869
ENSG00000163374ENST00000405763B0QZ55
ENSG00000163374ENST00000407221Q9H869
ENSG00000163374ENST00000436865F8WD62
ENSG00000163374ENST00000443231A3KFK1
ENSG00000163374ENST00000454523A3KFK2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
351217382022ROCK1 mechano-signaling dependency of human malignancies driven by TEAD/YAP activation.16
351217382022ROCK1 mechano-signaling dependency of human malignancies driven by TEAD/YAP activation.16
339719762021Whole genome sequencing reveals a frameshift mutation and a large deletion in YY1AP1 in a girl with a panvascular artery disease.2
348085022021KAT6A is associated with sorafenib resistance and contributes to progression of hepatocellular carcinoma by targeting YAP.8
339719762021Whole genome sequencing reveals a frameshift mutation and a large deletion in YY1AP1 in a girl with a panvascular artery disease.2
348085022021KAT6A is associated with sorafenib resistance and contributes to progression of hepatocellular carcinoma by targeting YAP.8
319897432020Prostaglandin E(2) and its receptor EP2 trigger signaling that contributes to YAP-mediated cell competition.7
331552072020CUL4A promotes proliferation and inhibits apoptosis of colon cancer cells via regulating Hippo pathway.4
319897432020Prostaglandin E(2) and its receptor EP2 trigger signaling that contributes to YAP-mediated cell competition.7
331552072020CUL4A promotes proliferation and inhibits apoptosis of colon cancer cells via regulating Hippo pathway.4
305562932019Identification of pathogenic YY1AP1 splice variants in siblings with Grange syndrome by whole exome sequencing.5
312703752019Hemorrhagic stroke and renovascular hypertension with Grange syndrome arising from a novel pathogenic variant in YY1AP1.6
314815322019YAP and TAZ regulate cell volume.24
305562932019Identification of pathogenic YY1AP1 splice variants in siblings with Grange syndrome by whole exome sequencing.5
312703752019Hemorrhagic stroke and renovascular hypertension with Grange syndrome arising from a novel pathogenic variant in YY1AP1.6

Citation

Dessen P

YY1AP1 (YY1 associated protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/42854