Identity
HGNC
LOCATION
18p11.32
LOCUSID
ALIAS
HsT441,P61-YES,Yes,c-yes
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7525
MIM: 164880
HGNC: 12841
Ensembl: ENSG00000176105
Variants:
dbSNP: 7525
ClinVar: 7525
TCGA: ENSG00000176105
COSMIC: YES1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000176105 | ENST00000314574 | P07947 |
| ENSG00000176105 | ENST00000577961 | J3QRU1 |
| ENSG00000176105 | ENST00000584307 | P07947 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37009887 | 2023 | Downregulation of circ-YES1 suppresses NSCLC migration and proliferation through the miR-142-3p-HMGB1 axis. | 3 |
| 37371529 | 2023 | YES1 Kinase Mediates the Membrane Removal of Rescued F508del-CFTR in Airway Cells by Promoting MAPK Pathway Activation via SHC1. | 1 |
| 37009887 | 2023 | Downregulation of circ-YES1 suppresses NSCLC migration and proliferation through the miR-142-3p-HMGB1 axis. | 3 |
| 37371529 | 2023 | YES1 Kinase Mediates the Membrane Removal of Rescued F508del-CFTR in Airway Cells by Promoting MAPK Pathway Activation via SHC1. | 1 |
| 35015027 | 2022 | Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribrosa Cells in Glaucoma. | 11 |
| 35988891 | 2022 | YES1 Is a Druggable Oncogenic Target in SCLC. | 6 |
| 35015027 | 2022 | Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribrosa Cells in Glaucoma. | 11 |
| 35988891 | 2022 | YES1 Is a Druggable Oncogenic Target in SCLC. | 6 |
| 33730553 | 2021 | Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation. | 5 |
| 33941853 | 2021 | EphA2-YES1-ANXA2 pathway promotes gastric cancer progression and metastasis. | 19 |
| 33730553 | 2021 | Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation. | 5 |
| 33941853 | 2021 | EphA2-YES1-ANXA2 pathway promotes gastric cancer progression and metastasis. | 19 |
| 31794020 | 2020 | Genome-Wide Analysis Identifies Two Susceptibility Loci for Positive Thyroid Peroxidase and Thyroglobulin Antibodies. | 3 |
| 31856375 | 2020 | YES1 activation induces acquired resistance to neratinib in HER2-amplified breast and lung cancers. | 13 |
| 31970720 | 2020 | Overexpression of YES1 is associated with favorable prognosis and increased platinum-sensitivity in patients with epithelial ovarian cancer. | 4 |
Citation
Dessen P
YES1 (YES proto-oncogene 1, Src family tyrosine kinase)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42856/yes1
