Identity
HGNC
LOCATION
1q21.2
LOCUSID
ALIAS
CEZANNE,ZA20D1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56957
MIM: 611748
HGNC: 16683
Ensembl: ENSG00000264522
Variants:
dbSNP: 56957
ClinVar: 56957
TCGA: ENSG00000264522
COSMIC: OTUD7B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000264522 | ENST00000417191 | Q5SZ59 |
| ENSG00000264522 | ENST00000581312 | Q6GQQ9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37429790 | 2024 | OTUD7B deubiquitinates and stabilizes YAP1 to upregulate NUAK2 expression, thus accelerating gastric cancer procession. | 2 |
| 38088504 | 2024 | OTU deubiquitinase 7B facilitates the hyperthermia-induced inhibition of lung cancer progression through enhancing Smac-mediated mitochondrial dysfunction. | 1 |
| 37429790 | 2024 | OTUD7B deubiquitinates and stabilizes YAP1 to upregulate NUAK2 expression, thus accelerating gastric cancer procession. | 2 |
| 38088504 | 2024 | OTU deubiquitinase 7B facilitates the hyperthermia-induced inhibition of lung cancer progression through enhancing Smac-mediated mitochondrial dysfunction. | 1 |
| 37516734 | 2023 | The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2. | 0 |
| 37516734 | 2023 | The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2. | 0 |
| 33599243 | 2022 | Cezanne is a critical regulator of pathological arterial remodelling by targeting β-catenin signalling. | 9 |
| 33599243 | 2022 | Cezanne is a critical regulator of pathological arterial remodelling by targeting β-catenin signalling. | 9 |
| 34035221 | 2021 | OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation. | 14 |
| 34035221 | 2021 | OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation. | 14 |
| 31937588 | 2020 | Oxygen-dependent asparagine hydroxylation of the ubiquitin-associated (UBA) domain in Cezanne regulates ubiquitin binding. | 9 |
| 31937588 | 2020 | Oxygen-dependent asparagine hydroxylation of the ubiquitin-associated (UBA) domain in Cezanne regulates ubiquitin binding. | 9 |
| 31699778 | 2019 | Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne. | 16 |
| 31747939 | 2019 | Long noncoding RNA 00976 promotes pancreatic cancer progression through OTUD7B by sponging miR-137 involving EGFR/MAPK pathway. | 43 |
| 31699778 | 2019 | Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne. | 16 |
Citation
Dessen P
OTUD7B (OTU deubiquitinase 7B)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/42862/otud7b
