Identity
HGNC
LOCATION
1p34.2
LOCUSID
ALIAS
FACE-1,FACE1,HGPS,PRO1,STE24,Ste24p
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10269
MIM: 606480
HGNC: 12877
Ensembl: ENSG00000084073
Variants:
dbSNP: 10269
ClinVar: 10269
TCGA: ENSG00000084073
COSMIC: ZMPSTE24
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000084073 | ENST00000372759 | O75844 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Terpenoid backbone biosynthesis | KEGG | ko00900 |
| Terpenoid backbone biosynthesis | KEGG | hsa00900 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37270786 | 2023 | Analysis of a non-lethal biallelic frameshift mutation in ZMPSTE24 reveals utilization of alternative translation initiation codons. | 0 |
| 37885131 | 2023 | Prelamin A and ZMPSTE24 in premature and physiological aging. | 2 |
| 37270786 | 2023 | Analysis of a non-lethal biallelic frameshift mutation in ZMPSTE24 reveals utilization of alternative translation initiation codons. | 0 |
| 37885131 | 2023 | Prelamin A and ZMPSTE24 in premature and physiological aging. | 2 |
| 35597529 | 2022 | An exceptional biallelic N-terminal frame shift mutation in ZMPSTE24 leads to non-lethal progeria due to possible utilization of a downstream alternative start codon. | 0 |
| 36197088 | 2022 | The Integral Membrane Protein ZMPSTE24 Protects Cells from SARS-CoV-2 Spike-Mediated Pseudovirus Infection and Syncytia Formation. | 7 |
| 35597529 | 2022 | An exceptional biallelic N-terminal frame shift mutation in ZMPSTE24 leads to non-lethal progeria due to possible utilization of a downstream alternative start codon. | 0 |
| 36197088 | 2022 | The Integral Membrane Protein ZMPSTE24 Protects Cells from SARS-CoV-2 Spike-Mediated Pseudovirus Infection and Syncytia Formation. | 7 |
| 32799420 | 2021 | Protein structural and mechanistic basis of progeroid laminopathies. | 16 |
| 33130089 | 2021 | OMA1-An integral membrane protease? | 11 |
| 33293369 | 2021 | Site specificity determinants for prelamin A cleavage by the zinc metalloprotease ZMPSTE24. | 6 |
| 34003736 | 2021 | ZMPSTE24 Regulates SARS-CoV-2 Spike Protein-enhanced Expression of Endothelial PAI-1. | 20 |
| 34647350 | 2021 | Restrictive dermopathy: Three new patients with ZMPSTE24 mutations and a review of the literature. | 0 |
| 32799420 | 2021 | Protein structural and mechanistic basis of progeroid laminopathies. | 16 |
| 33130089 | 2021 | OMA1-An integral membrane protease? | 11 |
Citation
Dessen P
ZMPSTE24 (zinc metallopeptidase STE24)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42868/zmpste24
