Identity
HGNC
LOCATION
2p22.2
LOCUSID
ALIAS
EPK2,PKC-NU,PKD3,PRKCN,nPKC-NU
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23683
MIM: 607077
HGNC: 9408
Ensembl: ENSG00000115825
Variants:
dbSNP: 23683
ClinVar: 23683
TCGA: ENSG00000115825
COSMIC: PRKD3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36672148 | 2023 | Protein Kinase D3 (PKD3) Requires Hsp90 for Stability and Promotion of Prostate Cancer Cell Migration. | 1 |
| 36672148 | 2023 | Protein Kinase D3 (PKD3) Requires Hsp90 for Stability and Promotion of Prostate Cancer Cell Migration. | 1 |
| 31745977 | 2020 | The GEF-H1/PKD3 signaling pathway promotes the maintenance of triple-negative breast cancer stem cells. | 9 |
| 31944568 | 2020 | Protein Kinase D3 promotes the cell proliferation by activating the ERK1/c-MYC axis in breast cancer. | 14 |
| 32048304 | 2020 | Deletion of Protein Kinase D3 Promotes Liver Fibrosis in Mice. | 18 |
| 32319563 | 2020 | Protein kinase D3 regulates the expression of the immunosuppressive protein, PD‑L1, through STAT1/STAT3 signaling. | 14 |
| 33378018 | 2020 | PRKD3 promotes malignant progression of OSCC by downregulating KLF16 expression. | 2 |
| 31745977 | 2020 | The GEF-H1/PKD3 signaling pathway promotes the maintenance of triple-negative breast cancer stem cells. | 9 |
| 31944568 | 2020 | Protein Kinase D3 promotes the cell proliferation by activating the ERK1/c-MYC axis in breast cancer. | 14 |
| 32048304 | 2020 | Deletion of Protein Kinase D3 Promotes Liver Fibrosis in Mice. | 18 |
| 32319563 | 2020 | Protein kinase D3 regulates the expression of the immunosuppressive protein, PD‑L1, through STAT1/STAT3 signaling. | 14 |
| 33378018 | 2020 | PRKD3 promotes malignant progression of OSCC by downregulating KLF16 expression. | 2 |
| 30652415 | 2019 | Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer. | 8 |
| 30841931 | 2019 | Protein kinase Ds promote tumor angiogenesis through mast cell recruitment and expression of angiogenic factors in prostate cancer microenvironment. | 24 |
| 31026442 | 2019 | Protein kinase D3 promotes gastric cancer development through p65/6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 activation of glycolysis. | 8 |
Citation
Dessen P
PRKD3 (protein kinase D3)
Atlas Genet Cytogenet Oncol Haematol. 2004-06-01
Online version: http://atlasgeneticsoncology.org/gene/42900/prkd3
