TP53INP2 (tumor protein p53 inducible nuclear protein 2)

2004-08-01  

Identity

HGNC
TP53INP2
LOCATION
20q11.22
LOCUSID
58476
ALIAS
C20orf110,DOR,PIG-U,PIGU,PINH,dJ1181N3.1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 58476
MIM: 617549
HGNC: 16104
Ensembl: ENSG00000078804

Variants:

dbSNP: 58476
ClinVar: 58476
TCGA: ENSG00000078804
COSMIC: TP53INP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000078804ENST00000374809Q8IXH6
ENSG00000078804ENST00000374810Q8IXH6
ENSG00000078804ENST00000414082Q5JX66
ENSG00000078804ENST00000451665Q5JX65

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900
1000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140

References

Pubmed IDYearTitleCitations
379954532024TP53INP2 modulates the malignant progression of colorectal cancer by reducing the inactive form of β-catenin.0
379954532024TP53INP2 modulates the malignant progression of colorectal cancer by reducing the inactive form of β-catenin.0
366505732023Inactivation of ZSCAN18 by promoter hypermethylation drives the proliferation via attenuating TP53INP2-mediated autophagy in gastric cancer cells.5
366751342023Cytoplasmic Expression of TP53INP2 Modulated by Demethylase FTO and Mutant NPM1 Promotes Autophagy in Leukemia Cells.8
366505732023Inactivation of ZSCAN18 by promoter hypermethylation drives the proliferation via attenuating TP53INP2-mediated autophagy in gastric cancer cells.5
366751342023Cytoplasmic Expression of TP53INP2 Modulated by Demethylase FTO and Mutant NPM1 Promotes Autophagy in Leukemia Cells.8
356155332022Overexpression of TP53INP2 Promotes Apoptosis in Clear Cell Renal Cell Cancer via Caspase-8/TRAF6 Signaling Pathway.4
359542302022TP53INP2 Contributes to TGF-β2-Induced Autophagy during the Epithelial-Mesenchymal Transition in Posterior Capsular Opacification Development.4
356155332022Overexpression of TP53INP2 Promotes Apoptosis in Clear Cell Renal Cell Cancer via Caspase-8/TRAF6 Signaling Pathway.4
359542302022TP53INP2 Contributes to TGF-β2-Induced Autophagy during the Epithelial-Mesenchymal Transition in Posterior Capsular Opacification Development.4
319316582020The bifunctional role of TP53INP2 in transcription and autophagy.10
325350702020Dysregulation in the expression of (lncRNA-TSIX, TP53INP2 mRNA, miRNA-1283) in spinal cord injury.5
319316582020The bifunctional role of TP53INP2 in transcription and autophagy.10
325350702020Dysregulation in the expression of (lncRNA-TSIX, TP53INP2 mRNA, miRNA-1283) in spinal cord injury.5
307677042019TP53INP2 contributes to autophagosome formation by promoting LC3-ATG7 interaction.39

Citation

Dessen P

TP53INP2 (tumor protein p53 inducible nuclear protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2004-08-01

Online version: http://atlasgeneticsoncology.org/gene/42920