DPP9 (dipeptidyl peptidase 9)

2004-11-01  

Identity

HGNC
DPP9
LOCATION
19p13.3
LOCUSID
91039
ALIAS
DP9,DPLP9,DPP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 91039
MIM: 608258
HGNC: 18648
Ensembl: ENSG00000142002

Variants:

dbSNP: 91039
ClinVar: 91039
TCGA: ENSG00000142002
COSMIC: DPP9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000142002ENST00000262960Q86TI2
ENSG00000142002ENST00000593973M0QXN4
ENSG00000142002ENST00000594671Q86TI2
ENSG00000142002ENST00000595327M0R1L4
ENSG00000142002ENST00000597726M0R3E8
ENSG00000142002ENST00000597849M0R2A8
ENSG00000142002ENST00000597900M0R334
ENSG00000142002ENST00000598041M0QXG6
ENSG00000142002ENST00000598360M0R0I1
ENSG00000142002ENST00000598800Q86TI2
ENSG00000142002ENST00000599163M0R162
ENSG00000142002ENST00000599248M0QXA6
ENSG00000142002ENST00000600556M0QZ97
ENSG00000142002ENST00000600621M0R2G6
ENSG00000142002ENST00000601130M0R145
ENSG00000142002ENST00000601720M0QXI5
ENSG00000142002ENST00000602161M0R3C4
ENSG00000142002ENST00000646573A0A2R8YF65

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
384583392024DPP8/9 inhibition attenuates the TGF-β1-induced excessive deposition of extracellular matrix (ECM) in human mesangial cells via Smad and Akt signaling pathways.0
385314822024Dipeptidyl-peptidase 9 regulates the dynamics of tumorigenesis and metastasis in breast cancer.0
384583392024DPP8/9 inhibition attenuates the TGF-β1-induced excessive deposition of extracellular matrix (ECM) in human mesangial cells via Smad and Akt signaling pathways.0
385314822024Dipeptidyl-peptidase 9 regulates the dynamics of tumorigenesis and metastasis in breast cancer.0
375444112023Hemophagocytic lymphohistiocytosis-like hyperinflammation due to a de novo mutation in DPP9.1
377135962023DPP9 Stabilizes NRF2 to Suppress Ferroptosis and Induce Sorafenib Resistance in Clear Cell Renal Cell Carcinoma.7
375444112023Hemophagocytic lymphohistiocytosis-like hyperinflammation due to a de novo mutation in DPP9.1
377135962023DPP9 Stabilizes NRF2 to Suppress Ferroptosis and Induce Sorafenib Resistance in Clear Cell Renal Cell Carcinoma.7
351315432022CCR2 and DPP9 expression in the peripheral blood of COVID-19 patients: Influences of the disease severity and gender.11
363090852022Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain.2
351315432022CCR2 and DPP9 expression in the peripheral blood of COVID-19 patients: Influences of the disease severity and gender.11
363090852022Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain.2
337319292021Structural and biochemical mechanisms of NLRP1 inhibition by DPP9.64
337319322021DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation.74
337859222021DPP9 restrains NLRP1 activation.4

Citation

Dessen P

DPP9 (dipeptidyl peptidase 9)

Atlas Genet Cytogenet Oncol Haematol. 2004-11-01

Online version: http://atlasgeneticsoncology.org/gene/42928/meetings/favicon/cancer-prone-explorer/