Identity
HGNC
LOCATION
15q15.1
LOCUSID
ALIAS
TLP,VAM6,hVam6p
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23339
MIM: 612188
HGNC: 20593
Ensembl: ENSG00000166887
Variants:
dbSNP: 23339
ClinVar: 23339
TCGA: ENSG00000166887
COSMIC: VPS39
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166887 | ENST00000318006 | Q96JC1 |
| ENSG00000166887 | ENST00000318006 | A0A024R9L9 |
| ENSG00000166887 | ENST00000348544 | Q96JC1 |
| ENSG00000166887 | ENST00000564994 | H3BTU0 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33893273 | 2021 | VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics. | 15 |
| 33893273 | 2021 | VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics. | 15 |
| 25655281 | 2015 | Functional characterization of TRAP1-like protein involved in modulating fibrotic processes mediated by TGF-β/Smad signaling in hypertrophic scar fibroblasts. | 9 |
| 25655281 | 2015 | Functional characterization of TRAP1-like protein involved in modulating fibrotic processes mediated by TGF-β/Smad signaling in hypertrophic scar fibroblasts. | 9 |
| 23167963 | 2013 | The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion. | 57 |
| 23418473 | 2013 | Effects of TRAP-1-like protein (TLP) gene on collagen synthesis induced by TGF-β/Smad signaling in human dermal fibroblasts. | 14 |
| 23167963 | 2013 | The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion. | 57 |
| 23418473 | 2013 | Effects of TRAP-1-like protein (TLP) gene on collagen synthesis induced by TGF-β/Smad signaling in human dermal fibroblasts. | 14 |
| 21454559 | 2011 | Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus. | 37 |
| 21454559 | 2011 | Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus. | 37 |
| 20363736 | 2010 | Differential effects of TBC1D15 and mammalian Vps39 on Rab7 activation state, lysosomal morphology, and growth factor dependence. | 67 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20363736 | 2010 | Differential effects of TBC1D15 and mammalian Vps39 on Rab7 activation state, lysosomal morphology, and growth factor dependence. | 67 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
Citation
Dessen P
VPS39 (VPS39 subunit of HOPS complex)
Atlas Genet Cytogenet Oncol Haematol. 2004-11-01
Online version: http://atlasgeneticsoncology.org/gene/42957/vps39
