OMD (osteomodulin)

2007-03-01  

Identity

HGNC
OMD
LOCATION
9q22.31
LOCUSID
4958
ALIAS
OSAD,SLRR2C
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4958
MIM: 618926
HGNC: 8134
Ensembl: ENSG00000127083

Variants:

dbSNP: 4958
ClinVar: 4958
TCGA: ENSG00000127083
COSMIC: OMD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127083ENST00000375550Q99983

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
DiseaseREACTOMER-HSA-1643685
Diseases of glycosylationREACTOMER-HSA-3781865
Diseases associated with glycosaminoglycan metabolismREACTOMER-HSA-3560782
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)REACTOMER-HSA-3656244
Defective CHST6 causes MCDC1REACTOMER-HSA-3656225
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Keratan sulfate/keratin metabolismREACTOMER-HSA-1638074
Keratan sulfate biosynthesisREACTOMER-HSA-2022854
Keratan sulfate degradationREACTOMER-HSA-2022857
Defective ST3GAL3 causes MCT12 and EIEE15REACTOMER-HSA-3656243

References

Pubmed IDYearTitleCitations
370174252023Osteomodulin contributes to keloid development by regulating p38 MAPK signaling.0
370174252023Osteomodulin contributes to keloid development by regulating p38 MAPK signaling.0
351353202022Osteomodulin Gene Expression Is Associated With Plaque Calcification, Stability, and Fewer Cardiovascular Events in the CPIP Cohort.4
351353202022Osteomodulin Gene Expression Is Associated With Plaque Calcification, Stability, and Fewer Cardiovascular Events in the CPIP Cohort.4
337151372021Osteomodulin is a Potential Genetic Target for Hypertrophic Cardiomyopathy.5
337151372021Osteomodulin is a Potential Genetic Target for Hypertrophic Cardiomyopathy.5
253713142015Distinct dysregulation of the small leucine-rich repeat protein family in osteoarthritic acetabular labrum compared to articular cartilage.10
260037322015Osteomodulin regulates diameter and alters shape of collagen fibrils.21
253713142015Distinct dysregulation of the small leucine-rich repeat protein family in osteoarthritic acetabular labrum compared to articular cartilage.10
260037322015Osteomodulin regulates diameter and alters shape of collagen fibrils.21
197007672009The tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteoadherin bind motifs of basic clusters in a variety of heparin-binding proteins, including bioactive factors.24
197007672009The tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteoadherin bind motifs of basic clusters in a variety of heparin-binding proteins, including bioactive factors.24
124891792002TGF beta 1 signaling and stimulation of osteoadherin in human odontoblasts in vitro.2
124891792002TGF beta 1 signaling and stimulation of osteoadherin in human odontoblasts in vitro.2

Citation

Dessen P

OMD (osteomodulin)

Atlas Genet Cytogenet Oncol Haematol. 2007-03-01

Online version: http://atlasgeneticsoncology.org/gene/42962/gene-fusions/css/lib/deep-insight-explorer/