NEIL3 (nei like DNA glycosylase 3)

2005-02-01  

Identity

HGNC
NEIL3
LOCATION
4q34.3
LOCUSID
55247
ALIAS
FGP2,FPG2,NEI3,ZGRF3,hFPG2,hNEI3

Other Information

Locus ID:

NCBI: 55247
MIM: 608934
HGNC: 24573
Ensembl: ENSG00000109674

Variants:

dbSNP: 55247
ClinVar: 55247
TCGA: ENSG00000109674
COSMIC: NEIL3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109674ENST00000264596Q8TAT5
ENSG00000109674ENST00000513321D6RAV1

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Base excision repairKEGGko03410
Base excision repairKEGGhsa03410

References

Pubmed IDYearTitleCitations
379925672024NEIL3 promotes cell proliferation of ccRCC via the cyclin D1-Rb-E2F1 feedback loop regulation.0
379925672024NEIL3 promotes cell proliferation of ccRCC via the cyclin D1-Rb-E2F1 feedback loop regulation.0
378720952023[Overexpression of Nei endonuclease VIII-like protein 3 in hepatocellular carcinoma indicates increased levels of immune infiltration and an unfavorable prognosis].0
378720952023[Overexpression of Nei endonuclease VIII-like protein 3 in hepatocellular carcinoma indicates increased levels of immune infiltration and an unfavorable prognosis].0
350310582022EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3.104
350310582022EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3.104
337145522021DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development.8
337503892021CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-I RNA-editing.62
339210352021Deficiency of NEIL3 Enhances the Chemotherapy Resistance of Prostate Cancer.10
337145522021DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development.8
337503892021CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-I RNA-editing.62
339210352021Deficiency of NEIL3 Enhances the Chemotherapy Resistance of Prostate Cancer.10
319808152020Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair.41
328789892020An autoinhibitory role for the GRF zinc finger domain of DNA glycosylase NEIL3.11
319808152020Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair.41

Citation

Dessen P

NEIL3 (nei like DNA glycosylase 3)

Atlas Genet Cytogenet Oncol Haematol. 2005-02-01

Online version: http://atlasgeneticsoncology.org/gene/43003