TNFAIP8L1 (TNF alpha induced protein 8 like 1)

2005-11-01  

Identity

HGNC
TNFAIP8L1
LOCATION
19p13.3
LOCUSID
126282
ALIAS
TIPE1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 126282
MIM: 615869
HGNC: 28279
Ensembl: ENSG00000185361

Variants:

dbSNP: 126282
ClinVar: 126282
TCGA: ENSG00000185361
COSMIC: TNFAIP8L1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185361ENST00000327473Q8WVP5
ENSG00000185361ENST00000536716Q8WVP5

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
PI MetabolismREACTOMER-HSA-1483255

References

Pubmed IDYearTitleCitations
364954662023TIPE1 inhibits the growth of Ewing's sarcoma cells by suppressing Wnt/β-catenin signaling.2
380658962023A pan-cancer analysis of TNFAIP8L1 in human tumors.0
364954662023TIPE1 inhibits the growth of Ewing's sarcoma cells by suppressing Wnt/β-catenin signaling.2
380658962023A pan-cancer analysis of TNFAIP8L1 in human tumors.0
351358092022Phosphoinositide-Binding Protein TIPE1 Promotes Alternative Activation of Macrophages and Tumor Progression via PIP3/Akt/TGFβ Axis.11
361510912022TIPE1 inhibits osteosarcoma tumorigenesis and progression by regulating PRMT1 mediated STAT3 arginine methylation.5
351358092022Phosphoinositide-Binding Protein TIPE1 Promotes Alternative Activation of Macrophages and Tumor Progression via PIP3/Akt/TGFβ Axis.11
361510912022TIPE1 inhibits osteosarcoma tumorigenesis and progression by regulating PRMT1 mediated STAT3 arginine methylation.5
337133582021TNF-α-Induce Protein 8-Like 1 Inhibits Hepatic Steatosis, Inflammation, and Fibrosis by Suppressing Polyubiquitination of Apoptosis Signal-Regulating Kinase 1.5
338959112021Human tumor necrosis factor alpha-induced protein eight-like 1 exhibited potent anti-tumor effect through modulation of proliferation, survival, migration and invasion of lung cancer cells.4
337133582021TNF-α-Induce Protein 8-Like 1 Inhibits Hepatic Steatosis, Inflammation, and Fibrosis by Suppressing Polyubiquitination of Apoptosis Signal-Regulating Kinase 1.5
338959112021Human tumor necrosis factor alpha-induced protein eight-like 1 exhibited potent anti-tumor effect through modulation of proliferation, survival, migration and invasion of lung cancer cells.4
311118742020TIPE1 impairs stemness maintenance in colorectal cancer through directly targeting β-catenin.6
316725502020TIPE1 accelerates atherogenesis by inducing endothelial dysfunction in response to oxidative stress.2
323298362020CDKN3 regulates cisplatin resistance to colorectal cancer through TIPE1.12

Citation

Dessen P

TNFAIP8L1 (TNF alpha induced protein 8 like 1)

Atlas Genet Cytogenet Oncol Haematol. 2005-11-01

Online version: http://atlasgeneticsoncology.org/gene/43042/tumors-explorer/gene-fusions/gene-explorer/