WTIP (WT1 interacting protein)

2005-11-01  

Identity

HGNC
WTIP
LOCATION
19q13.11
LOCUSID
126374
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 126374
MIM: 614790
HGNC: 20964
Ensembl: ENSG00000142279

Variants:

dbSNP: 126374
ClinVar: 126374
TCGA: ENSG00000142279
COSMIC: WTIP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000142279ENST00000585928K7EKM1
ENSG00000142279ENST00000590071A6NIX2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
Cellular responses to stressREACTOMER-HSA-2262752
Cellular response to hypoxiaREACTOMER-HSA-2262749
Regulation of Hypoxia-inducible Factor (HIF) by oxygenREACTOMER-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor AlphaREACTOMER-HSA-1234176
Hippo signaling pathway -multiple speciesKEGGko04392
Hippo signaling pathway -multiple speciesKEGGhsa04392

References

Pubmed IDYearTitleCitations
356710652022Wnt Signaling Interactor WTIP (Wilms Tumor Interacting Protein) Underlies Novel Mechanism for Cardiac Hypertrophy.0
356710652022Wnt Signaling Interactor WTIP (Wilms Tumor Interacting Protein) Underlies Novel Mechanism for Cardiac Hypertrophy.0
349309052021WTIP upregulates FOXO3a and induces apoptosis through PUMA in acute myeloid leukemia.4
349309052021WTIP upregulates FOXO3a and induces apoptosis through PUMA in acute myeloid leukemia.4
331082712020The S-phase-induced lncRNA SUNO1 promotes cell proliferation by controlling YAP1/Hippo signaling pathway.18
331082712020The S-phase-induced lncRNA SUNO1 promotes cell proliferation by controlling YAP1/Hippo signaling pathway.18
306908832019WT1-interacting protein inhibits cell proliferation and tumorigenicity in non-small-cell lung cancer via the AKT/FOXO1 axis.12
306908832019WT1-interacting protein inhibits cell proliferation and tumorigenicity in non-small-cell lung cancer via the AKT/FOXO1 axis.12
294402372018Tension-dependent regulation of mammalian Hippo signaling through LIMD1.53
301796022018Identification of the UBA2-WTIP fusion gene in acute myeloid leukemia.4
294402372018Tension-dependent regulation of mammalian Hippo signaling through LIMD1.53
301796022018Identification of the UBA2-WTIP fusion gene in acute myeloid leukemia.4
270337052016Nephrin Suppresses Hippo Signaling through the Adaptor Proteins Nck and WTIP.11
275357602016WTIP interacts with BRCA2 and is essential for BRCA2 centrosome localization in cervical cancer cell.4
270337052016Nephrin Suppresses Hippo Signaling through the Adaptor Proteins Nck and WTIP.11

Citation

Dessen P

WTIP (WT1 interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2005-11-01

Online version: http://atlasgeneticsoncology.org/gene/43046