ALKBH7 (alkB homolog 7)

2006-05-01  

Identity

HGNC
ALKBH7
LOCATION
19p13.3
LOCUSID
84266
ALIAS
ABH7,SPATA11,UNQ6002

Other Information

Locus ID:

NCBI: 84266
MIM: 613305
HGNC: 21306
Ensembl: ENSG00000125652

Variants:

dbSNP: 84266
ClinVar: 84266
TCGA: ENSG00000125652
COSMIC: ALKBH7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125652ENST00000245812Q9BT30
ENSG00000125652ENST00000596657M0QZH2
ENSG00000125652ENST00000599849M0QZI0

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383325762024Transformed astrocytes confer temozolomide resistance on glioblastoma via delivering ALKBH7 to enhance APNG expression after educating by glioblastoma stem cells-derived exosomes.1
383325762024Transformed astrocytes confer temozolomide resistance on glioblastoma via delivering ALKBH7 to enhance APNG expression after educating by glioblastoma stem cells-derived exosomes.1
342538972021ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing.36
342538972021ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing.36
282312802017ALKBH7 Variant Related to Prostate Cancer Exhibits Altered Substrate Binding.12
282312802017ALKBH7 Variant Related to Prostate Cancer Exhibits Altered Substrate Binding.12
251227572014The atomic resolution structure of human AlkB homolog 7 (ALKBH7), a key protein for programmed necrosis and fat metabolism.22
251227572014The atomic resolution structure of human AlkB homolog 7 (ALKBH7), a key protein for programmed necrosis and fat metabolism.22
236669232013Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis.38
236669232013Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis.38

Citation

Dessen P

ALKBH7 (alkB homolog 7)

Atlas Genet Cytogenet Oncol Haematol. 2006-05-01

Online version: http://atlasgeneticsoncology.org/gene/43081/tumors-explorer/meetings/js/template.js