Identity
HGNC
LOCATION
2p13.3
LOCUSID
ALIAS
HEL-S-308,KAIA0053
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9938
MIM: 610587
HGNC: 28951
Ensembl: ENSG00000163219
Variants:
dbSNP: 9938
ClinVar: 9938
TCGA: ENSG00000163219
COSMIC: ARHGAP25
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Rho GTPases | REACTOME | R-HSA-194315 |
| Rho GTPase cycle | REACTOME | R-HSA-194840 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37326327 | 2023 | ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop. | 2 |
| 37326327 | 2023 | ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop. | 2 |
| 36190314 | 2022 | A novel BRET-Based GAP assay reveals phosphorylation-dependent regulation of the RAC-specific GTPase activating protein ARHGAP25. | 0 |
| 36207695 | 2022 | Relationship between the expression of ARHGAP25 and RhoA in non-small cell lung cancer and vasculogenic mimicry. | 4 |
| 36190314 | 2022 | A novel BRET-Based GAP assay reveals phosphorylation-dependent regulation of the RAC-specific GTPase activating protein ARHGAP25. | 0 |
| 36207695 | 2022 | Relationship between the expression of ARHGAP25 and RhoA in non-small cell lung cancer and vasculogenic mimicry. | 4 |
| 33994864 | 2021 | ARHGAP25 Inhibits Pancreatic Adenocarcinoma Growth by Suppressing Glycolysis via AKT/mTOR Pathway. | 11 |
| 33994864 | 2021 | ARHGAP25 Inhibits Pancreatic Adenocarcinoma Growth by Suppressing Glycolysis via AKT/mTOR Pathway. | 11 |
| 31228451 | 2019 | ARHGAP25: A negative regulator of colorectal cancer (CRC) metastasis via the Wnt/β-catenin pathway. | 12 |
| 31228451 | 2019 | ARHGAP25: A negative regulator of colorectal cancer (CRC) metastasis via the Wnt/β-catenin pathway. | 12 |
| 19911011 | 2010 | Mutation of ARHGAP9 in patients with coronary spastic angina. | 0 |
| 19911011 | 2010 | Mutation of ARHGAP9 in patients with coronary spastic angina. | 0 |
Citation
Dessen P
ARHGAP25 (Rho GTPase activating protein 25)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43140/arhgap25
