LHX1 (LIM homeobox 1)

2011-06-01  

Identity

HGNC
LOCATION
17q12
LOCUSID
ALIAS
LIM-1,LIM1
FUSION GENES

Other Information

Locus ID:

NCBI: 3975
MIM: 601999
HGNC: 6593
Ensembl: ENSG00000273706

Variants:

dbSNP: 3975
ClinVar: 3975
TCGA: ENSG00000273706
COSMIC: LHX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000273706ENST00000614239P48742
ENSG00000273706ENST00000621767A0A087WY40

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
300764152019The Lim1 oncogene as a new therapeutic target for metastatic human renal cell carcinoma.8
300764152019The Lim1 oncogene as a new therapeutic target for metastatic human renal cell carcinoma.8
280614322017Identification and functional analysis of a novel LHX1 mutation associated with congenital absence of the uterus and vagina.8
286001062017Genetic analysis of Mayer-Rokitansky-Kuster-Hauser syndrome in a large cohort of families.23
280614322017Identification and functional analysis of a novel LHX1 mutation associated with congenital absence of the uterus and vagina.8
286001062017Genetic analysis of Mayer-Rokitansky-Kuster-Hauser syndrome in a large cohort of families.23
239540212013TBX6, LHX1 and copy number variations in the complex genetics of Müllerian aplasia.39
239540212013TBX6, LHX1 and copy number variations in the complex genetics of Müllerian aplasia.39
222179642012LHX1 mutation screening in 96 patients with müllerian duct abnormalities.6
222319132012Lim1/LIM1 is expressed in developing and adult mouse and human endometrium.4
227404942012Frame shift mutation of LHX1 is associated with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.31
228750242012Functional genomics identifies drivers of medulloblastoma dissemination.24
222179642012LHX1 mutation screening in 96 patients with müllerian duct abnormalities.6
222319132012Lim1/LIM1 is expressed in developing and adult mouse and human endometrium.4
227404942012Frame shift mutation of LHX1 is associated with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.31

Citation

Dessen P

LHX1 (LIM homeobox 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-06-01

Online version: http://atlasgeneticsoncology.org/gene/43146/gene-explorer/css/lib/meetings/