Identity
HGNC
LOCATION
3p14.3
LOCUSID
ALIAS
GEF3,STA3,XPLN
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 50650
MIM: 612115
HGNC: 683
Ensembl: ENSG00000163947
Variants:
dbSNP: 50650
ClinVar: 50650
TCGA: ENSG00000163947
COSMIC: ARHGEF3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36241648 | 2022 | ARHGEF3 regulates the stability of ACLY to promote the proliferation of lung cancer. | 2 |
| 36241648 | 2022 | ARHGEF3 regulates the stability of ACLY to promote the proliferation of lung cancer. | 2 |
| 34267198 | 2021 | Redefining the specificity of phosphoinositide-binding by human PH domain-containing proteins. | 23 |
| 34350290 | 2021 | ARHGEF3 Associated with Invasion, Metastasis, and Proliferation in Human Osteosarcoma. | 3 |
| 34267198 | 2021 | Redefining the specificity of phosphoinositide-binding by human PH domain-containing proteins. | 23 |
| 34350290 | 2021 | ARHGEF3 Associated with Invasion, Metastasis, and Proliferation in Human Osteosarcoma. | 3 |
| 32139661 | 2020 | Genetic variants in RET, ARHGEF3 and CTNNAL1, and relevant interaction networks, contribute to the risk of Hirschsprung disease. | 4 |
| 32139661 | 2020 | Genetic variants in RET, ARHGEF3 and CTNNAL1, and relevant interaction networks, contribute to the risk of Hirschsprung disease. | 4 |
| 29998287 | 2018 | DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies. | 55 |
| 29998287 | 2018 | DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies. | 55 |
| 28315487 | 2017 | XPLN is modulated by HDAC inhibitors and negatively regulates SPARC expression by targeting mTORC2 in human lung fibroblasts. | 8 |
| 28542600 | 2017 | SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume. | 11 |
| 28315487 | 2017 | XPLN is modulated by HDAC inhibitors and negatively regulates SPARC expression by targeting mTORC2 in human lung fibroblasts. | 8 |
| 28542600 | 2017 | SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume. | 11 |
| 27028992 | 2016 | The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis. | 14 |
Citation
Dessen P
ARHGEF3 (Rho guanine nucleotide exchange factor 3)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43151/arhgef3
