Identity
HGNC
LOCATION
11p15.5
LOCUSID
ALIAS
C11orf7,PEN11B,SAD1,SADA,STK29
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9024
MIM: 609236
HGNC: 11405
Ensembl: ENSG00000174672
Variants:
dbSNP: 9024
ClinVar: 9024
TCGA: ENSG00000174672
COSMIC: BRSK2
RNA/Proteins
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37188647 | 2023 | BRSK2 in pancreatic β cells promotes hyperinsulinemia-coupled insulin resistance and its genetic variants are associated with human type 2 diabetes. | 1 |
| 37188647 | 2023 | BRSK2 in pancreatic β cells promotes hyperinsulinemia-coupled insulin resistance and its genetic variants are associated with human type 2 diabetes. | 1 |
| 33500714 | 2021 | STK39 is a novel kinase contributing to the progression of hepatocellular carcinoma by the PLK1/ERK signaling pathway. | 18 |
| 33500714 | 2021 | STK39 is a novel kinase contributing to the progression of hepatocellular carcinoma by the PLK1/ERK signaling pathway. | 18 |
| 30879638 | 2019 | Deleterious Variation in BRSK2 Associates with a Neurodevelopmental Disorder. | 14 |
| 30879638 | 2019 | Deleterious Variation in BRSK2 Associates with a Neurodevelopmental Disorder. | 14 |
| 28591720 | 2017 | BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity. | 14 |
| 28591720 | 2017 | BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity. | 14 |
| 23907667 | 2013 | BRSK2 is a valosin-containing protein (VCP)-interacting protein that affects VCP functioning in endoplasmic reticulum-associated degradation. | 3 |
| 24047693 | 2013 | SAD-A and AMPK kinases: the "yin and yang" regulators of mTORC1 signaling in pancreatic β cells. | 5 |
| 23907667 | 2013 | BRSK2 is a valosin-containing protein (VCP)-interacting protein that affects VCP functioning in endoplasmic reticulum-associated degradation. | 3 |
| 24047693 | 2013 | SAD-A and AMPK kinases: the "yin and yang" regulators of mTORC1 signaling in pancreatic β cells. | 5 |
| 22609399 | 2012 | Jab1 interacts with brain-specific kinase 2 (BRSK2) and promotes its degradation in the ubiquitin-proteasome pathway. | 5 |
| 22713462 | 2012 | BRSK2 is regulated by ER stress in protein level and involved in ER stress-induced apoptosis. | 11 |
| 22798068 | 2012 | Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cells. | 25 |
Citation
Dessen P
BRSK2 (BR serine/threonine kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43174/brsk2
