CHN2 (chimerin 2)

2006-10-01  

Identity

HGNC
LOCATION
7p14.3
LOCUSID
ALIAS
ARHGAP3,BCH,CHN2-3,RHOGAP3
FUSION GENES

Other Information

Locus ID:

NCBI: 1124
MIM: 602857
HGNC: 1944
Ensembl: ENSG00000285162

Variants:

dbSNP: 1124
ClinVar: 1124
TCGA: ENSG00000285162
COSMIC: CHN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000285162ENST00000423511J3KSU2
ENSG00000285162ENST00000644824A0A2R8YEI5

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA128406956fluorouracilChemicalMultilinkAnnotationassociated24444404

References

Pubmed IDYearTitleCitations
371205752023Prenatal phthalate exposure and cord blood DNA methylation.1
371205752023Prenatal phthalate exposure and cord blood DNA methylation.1
340892732021Chemerin regulates formation and function of brown adipose tissue: Ablation results in increased insulin resistance with high fat challenge and aging.9
340892732021Chemerin regulates formation and function of brown adipose tissue: Ablation results in increased insulin resistance with high fat challenge and aging.9
315949172019Integrated genome-wide methylation and expression analyses reveal functional predictors of response to antidepressants.23
315949172019Integrated genome-wide methylation and expression analyses reveal functional predictors of response to antidepressants.23
281605562017Prognostic significance of serum chemerin levels in patients with non-small cell lung cancer.25
281605562017Prognostic significance of serum chemerin levels in patients with non-small cell lung cancer.25
270584242016A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression.10
270584242016A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression.10
263151102015Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility.21
263151102015Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility.21
248547632014Chimerin 2 genetic polymorphisms are associated with non-proliferative diabetic retinopathy in Taiwanese type 2 diabetic patients.6
250578522014Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma.24
248547632014Chimerin 2 genetic polymorphisms are associated with non-proliferative diabetic retinopathy in Taiwanese type 2 diabetic patients.6

Citation

Dessen P

CHN2 (chimerin 2)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43212