Identity
HGNC
LOCATION
2q33.1
LOCUSID
ALIAS
CLK,CLK/STY,STY
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1195
MIM: 601951
HGNC: 2068
Ensembl: ENSG00000013441
Variants:
dbSNP: 1195
ClinVar: 1195
TCGA: ENSG00000013441
COSMIC: CLK1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Legionellosis | KEGG | ko05134 |
| Legionellosis | KEGG | hsa05134 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37607329 | 2023 | Functions of SRPK, CLK and DYRK kinases in stem cells, development, and human developmental disorders. | 2 |
| 37607329 | 2023 | Functions of SRPK, CLK and DYRK kinases in stem cells, development, and human developmental disorders. | 2 |
| 32359191 | 2021 | A conserved sequence motif bridges two protein kinases for enhanced phosphorylation and nuclear function of a splicing factor. | 6 |
| 33811140 | 2021 | CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly. | 7 |
| 32359191 | 2021 | A conserved sequence motif bridges two protein kinases for enhanced phosphorylation and nuclear function of a splicing factor. | 6 |
| 33811140 | 2021 | CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly. | 7 |
| 31782550 | 2020 | LncRNA-dependent nuclear stress bodies promote intron retention through SR protein phosphorylation. | 60 |
| 32333232 | 2020 | Phosphoproteomic analysis identifies CLK1 as a novel therapeutic target in gastric cancer. | 20 |
| 31782550 | 2020 | LncRNA-dependent nuclear stress bodies promote intron retention through SR protein phosphorylation. | 60 |
| 32333232 | 2020 | Phosphoproteomic analysis identifies CLK1 as a novel therapeutic target in gastric cancer. | 20 |
| 31064840 | 2019 | Disordered protein interactions for an ordered cellular transition: Cdc2-like kinase 1 is transported to the nucleus via its Ser-Arg protein substrate. | 5 |
| 31064840 | 2019 | Disordered protein interactions for an ordered cellular transition: Cdc2-like kinase 1 is transported to the nucleus via its Ser-Arg protein substrate. | 5 |
| 29335301 | 2018 | Mobilization of a splicing factor through a nuclear kinase-kinase complex. | 18 |
| 29802995 | 2018 | Autoregulation of the human splice factor kinase CLK1 through exon skipping and intron retention. | 18 |
| 29335301 | 2018 | Mobilization of a splicing factor through a nuclear kinase-kinase complex. | 18 |
Citation
Dessen P
CLK1 (CDC like kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43215/clk1
