Identity
HGNC
LOCATION
13q13.3
LOCUSID
ALIAS
CL1,CLICK1,DCAMKL1,DCDC3A,DCLK
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9201
MIM: 604742
HGNC: 2700
Ensembl: ENSG00000133083
Variants:
dbSNP: 9201
ClinVar: 9201
TCGA: ENSG00000133083
COSMIC: DCLK1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38007147 | 2024 | DCLK1 and its oncogenic functions: A promising therapeutic target for cancers. | 1 |
| 38821583 | 2024 | DCLK1 Expression and its Functional Significance in Intrahepatic Cholangiocarcinoma and Bil-IN Stage. | 0 |
| 38007147 | 2024 | DCLK1 and its oncogenic functions: A promising therapeutic target for cancers. | 1 |
| 38821583 | 2024 | DCLK1 Expression and its Functional Significance in Intrahepatic Cholangiocarcinoma and Bil-IN Stage. | 0 |
| 36218231 | 2023 | Doublecortin-like kinase 1 is a therapeutic target in squamous cell carcinoma. | 4 |
| 37069669 | 2023 | Targeting DCLK1 attenuates tumor stemness and evokes antitumor immunity in triple-negative breast cancer by inhibiting IL-6/STAT3 signaling. | 6 |
| 37462016 | 2023 | [Doublecortin-like kinase 1 activates Hippo pathway to promote migration, invasion and proliferation of pancreatic cancer cells]. | 0 |
| 37487255 | 2023 | Exosomes from metastatic colon cancer cells drive the proliferation and migration of primary colon cancer through increased expression of cancer stem cell markers CD133 and DCLK1. | 4 |
| 37996782 | 2023 | Role of DCLK1/Hippo pathway in type II alveolar epithelial cells differentiation in acute respiratory distress syndrome. | 0 |
| 36218231 | 2023 | Doublecortin-like kinase 1 is a therapeutic target in squamous cell carcinoma. | 4 |
| 37069669 | 2023 | Targeting DCLK1 attenuates tumor stemness and evokes antitumor immunity in triple-negative breast cancer by inhibiting IL-6/STAT3 signaling. | 6 |
| 37462016 | 2023 | [Doublecortin-like kinase 1 activates Hippo pathway to promote migration, invasion and proliferation of pancreatic cancer cells]. | 0 |
| 37487255 | 2023 | Exosomes from metastatic colon cancer cells drive the proliferation and migration of primary colon cancer through increased expression of cancer stem cell markers CD133 and DCLK1. | 4 |
| 37996782 | 2023 | Role of DCLK1/Hippo pathway in type II alveolar epithelial cells differentiation in acute respiratory distress syndrome. | 0 |
| 35522902 | 2022 | Targeting DCLK1 overcomes 5-fluorouracil resistance in colorectal cancer through inhibiting CCAR1/β-catenin pathway-mediated cancer stemness. | 9 |
Citation
Dessen P
DCLK1 (doublecortin like kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43223/dclk1
