DYRK3 (dual specificity tyrosine phosphorylation regulated kinase 3)

2006-10-01  

Identity

HGNC
DYRK3
LOCATION
1q32.1
LOCUSID
8444
ALIAS
DYRK5,RED,REDK,hYAK3-2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8444
MIM: 603497
HGNC: 3094
Ensembl: ENSG00000143479

Variants:

dbSNP: 8444
ClinVar: 8444
TCGA: ENSG00000143479
COSMIC: DYRK3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143479ENST00000367106O43781
ENSG00000143479ENST00000367108O43781
ENSG00000143479ENST00000367109O43781
ENSG00000143479ENST00000441486Q5SY34
ENSG00000143479ENST00000649163A0A3B3ISB2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
385190312024Dual-specificity kinase DYRK3 phosphorylates p62 at the Thr-269 residue and promotes melanoma progression.0
385190312024Dual-specificity kinase DYRK3 phosphorylates p62 at the Thr-269 residue and promotes melanoma progression.0
338041692021Dual Specificity Kinase DYRK3 Promotes Aggressiveness of Glioblastoma by Altering Mitochondrial Morphology and Function.14
341475602021Protein quality control of DYRK family protein kinases by the Hsp90-Cdc37 molecular chaperone.3
341717982021DYRK3 contributes to differentiation and hypoxic control in neuroblastoma.5
342051232021Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinases (DYRKs) and cdc2-Like Kinases (CLKs) in Human Disease, an Overview.38
338041692021Dual Specificity Kinase DYRK3 Promotes Aggressiveness of Glioblastoma by Altering Mitochondrial Morphology and Function.14
341475602021Protein quality control of DYRK family protein kinases by the Hsp90-Cdc37 molecular chaperone.3
341717982021DYRK3 contributes to differentiation and hypoxic control in neuroblastoma.5
342051232021Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinases (DYRKs) and cdc2-Like Kinases (CLKs) in Human Disease, an Overview.38
296349192018Crystal Structure of Human Dual-Specificity Tyrosine-Regulated Kinase 3 Reveals New Structural Features and Insights into its Auto-phosphorylation.7
299737242018Kinase-controlled phase transition of membraneless organelles in mitosis.162
296349192018Crystal Structure of Human Dual-Specificity Tyrosine-Regulated Kinase 3 Reveals New Structural Features and Insights into its Auto-phosphorylation.7
299737242018Kinase-controlled phase transition of membraneless organelles in mitosis.162
234152272013Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling.285

Citation

Dessen P

DYRK3 (dual specificity tyrosine phosphorylation regulated kinase 3)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43237/dyrk3