FBXO8 (F-box protein 8)

2006-10-01  

Identity

HGNC
LOCATION
4q34.1
LOCUSID
ALIAS
DC10,FBS,FBX8

Other Information

Locus ID:

NCBI: 26269
MIM: 605649
HGNC: 13587
Ensembl: ENSG00000164117

Variants:

dbSNP: 26269
ClinVar: 26269
TCGA: ENSG00000164117
COSMIC: FBXO8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164117ENST00000393674Q9NRD0
ENSG00000164117ENST00000393674A0A0S2Z5D1
ENSG00000164117ENST00000503293Q9NRD0
ENSG00000164117ENST00000513696D6RIC0
ENSG00000164117ENST00000515664D6RJ92
ENSG00000164117ENST00000615392Q9NRD0

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383018582024FBXO8 is a novel prognostic biomarker in different molecular subtypes of breast cancer and suppresses breast cancer progression by targeting c-MYC.0
383018582024FBXO8 is a novel prognostic biomarker in different molecular subtypes of breast cancer and suppresses breast cancer progression by targeting c-MYC.0
327968132020FBX8 promotes metastatic dormancy of colorectal cancer in liver.8
327968132020FBX8 promotes metastatic dormancy of colorectal cancer in liver.8
310240082019FBX8 degrades GSTP1 through ubiquitination to suppress colorectal cancer progression.13
310240082019FBX8 degrades GSTP1 through ubiquitination to suppress colorectal cancer progression.13
279166062017FBX8 is a metastasis suppressor downstream of miR-223 and targeting mTOR for degradation in colorectal carcinoma.19
279166062017FBX8 is a metastasis suppressor downstream of miR-223 and targeting mTOR for degradation in colorectal carcinoma.19
258013342015Significance of FBX8 in progression of gastric cancer.5
258013342015Significance of FBX8 in progression of gastric cancer.5
255508532014Down-expression of F box only protein 8 correlates with tumor grade and poor prognosis in human glioma.2
255508532014Down-expression of F box only protein 8 correlates with tumor grade and poor prognosis in human glioma.2
238260802013FBX8 Acts as an Invasion and Metastasis Suppressor and Correlates with Poor Survival in Hepatocellular Carcinoma.7
238260802013FBX8 Acts as an Invasion and Metastasis Suppressor and Correlates with Poor Survival in Hepatocellular Carcinoma.7
208482312010c-Myc stimulates cell invasion by inhibiting FBX8 function.10

Citation

Dessen P

FBXO8 (F-box protein 8)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43256/fbxo8