Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3656
MIM: 603304
HGNC: 6113
Ensembl: ENSG00000134070
Variants:
dbSNP: 3656
ClinVar: 3656
TCGA: ENSG00000134070
COSMIC: IRAK2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000134070 | ENST00000256458 | O43187 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35588430 | 2022 | Multi-locus SNP analyses of interleukin 1 receptor associated kinases 2 gene polymorphisms with the susceptibility to rheumatoid arthritis. | 2 |
| 35588430 | 2022 | Multi-locus SNP analyses of interleukin 1 receptor associated kinases 2 gene polymorphisms with the susceptibility to rheumatoid arthritis. | 2 |
| 33799071 | 2021 | The extreme C-terminus of IRAK2 assures full TRAF6 ubiquitination and optimal TLR signaling. | 3 |
| 33864770 | 2021 | IRAK2 Has a Critical Role in Promoting Feed-Forward Amplification of Epidermal Inflammatory Responses. | 9 |
| 33799071 | 2021 | The extreme C-terminus of IRAK2 assures full TRAF6 ubiquitination and optimal TLR signaling. | 3 |
| 33864770 | 2021 | IRAK2 Has a Critical Role in Promoting Feed-Forward Amplification of Epidermal Inflammatory Responses. | 9 |
| 31650390 | 2020 | IRAK2 is associated with systemic lupus erythematosus risk. | 1 |
| 31995744 | 2020 | MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling. | 28 |
| 31650390 | 2020 | IRAK2 is associated with systemic lupus erythematosus risk. | 1 |
| 31995744 | 2020 | MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling. | 28 |
| 31073143 | 2019 | IRAK2 and TLR10 confer risk of Hashimoto's disease: a genetic association study based on the Han Chinese population. | 3 |
| 31073143 | 2019 | IRAK2 and TLR10 confer risk of Hashimoto's disease: a genetic association study based on the Han Chinese population. | 3 |
| 29129009 | 2018 | IRAK2 is associated with susceptibility to rheumatoid arthritis. | 1 |
| 29753111 | 2018 | IRAK2 counterbalances oncogenic Smurf1 in colon cancer cells by dictating ER stress. | 11 |
| 29978465 | 2018 | Genetic variant of IRAK2 in the toll-like receptor signaling pathway and survival of non-small cell lung cancer. | 10 |
Citation
Dessen P
IRAK2 (interleukin 1 receptor associated kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43327/irak2
