Identity
HGNC
LOCATION
7q21.3
LOCUSID
ALIAS
AATYK2,BREK,KPI-2,KPI2,LMR2,PPP1R100,cprk,hBREK
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22853
MIM: 610989
HGNC: 17880
Ensembl: ENSG00000164715
Variants:
dbSNP: 22853
ClinVar: 22853
TCGA: ENSG00000164715
COSMIC: LMTK2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164715 | ENST00000297293 | Q8IWU2 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37271222 | 2023 | Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway. | 2 |
| 37271222 | 2023 | Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway. | 2 |
| 31068217 | 2019 | LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer's disease brains. | 12 |
| 31395338 | 2019 | Silencing of lemur tyrosine kinase 2 restricts the proliferation and invasion of hepatocellular carcinoma through modulation of GSK-3β/Wnt/β-catenin signaling. | 5 |
| 31722712 | 2019 | circLMTK2 acts as a sponge of miR-150-5p and promotes proliferation and metastasis in gastric cancer. | 43 |
| 31748522 | 2019 | Neuropathological characterization of Lemur tyrosine kinase 2 (LMTK2) in Alzheimer's disease and neocortical Lewy body disease. | 9 |
| 31068217 | 2019 | LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer's disease brains. | 12 |
| 31395338 | 2019 | Silencing of lemur tyrosine kinase 2 restricts the proliferation and invasion of hepatocellular carcinoma through modulation of GSK-3β/Wnt/β-catenin signaling. | 5 |
| 31722712 | 2019 | circLMTK2 acts as a sponge of miR-150-5p and promotes proliferation and metastasis in gastric cancer. | 43 |
| 31748522 | 2019 | Neuropathological characterization of Lemur tyrosine kinase 2 (LMTK2) in Alzheimer's disease and neocortical Lewy body disease. | 9 |
| 28040547 | 2017 | Lemur tyrosine kinase 2 (LMTK2) is a determinant of cell sensitivity to apoptosis by regulating the levels of the BCL2 family members. | 14 |
| 28040547 | 2017 | Lemur tyrosine kinase 2 (LMTK2) is a determinant of cell sensitivity to apoptosis by regulating the levels of the BCL2 family members. | 14 |
| 26008968 | 2015 | Lemur Tyrosine Kinase 2, a novel target in prostate cancer therapy. | 14 |
| 26559041 | 2015 | Signal dependent ER export of lemur tyrosine kinase 2. | 2 |
| 26008968 | 2015 | Lemur Tyrosine Kinase 2, a novel target in prostate cancer therapy. | 14 |
Citation
Dessen P
LMTK2 (lemur tyrosine kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43337/lmtk2
