Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84930
MIM: 608221
HGNC: 19042
Ensembl: ENSG00000120539
Variants:
dbSNP: 84930
ClinVar: 84930
TCGA: ENSG00000120539
COSMIC: MASTL
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000120539 | ENST00000342386 | Q96GX5 |
| ENSG00000120539 | ENST00000375940 | Q96GX5 |
| ENSG00000120539 | ENST00000375946 | Q96GX5 |
| ENSG00000120539 | ENST00000477034 | A0A087WUU7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35732702 | 2022 | SILAC kinase screen identifies potential MASTL substrates. | 2 |
| 35732702 | 2022 | SILAC kinase screen identifies potential MASTL substrates. | 2 |
| 33582914 | 2021 | Knockdown of Microtubule Associated Serine/threonine Kinase Like Expression Inhibits Gastric Cancer Cell Growth and Induces Apoptosis by Activation of ERK1/2 and Inactivation of NF-κB Signaling. | 2 |
| 33627787 | 2021 | Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers. | 18 |
| 34331012 | 2021 | MASTL regulates EGFR signaling to impact pancreatic cancer progression. | 6 |
| 33582914 | 2021 | Knockdown of Microtubule Associated Serine/threonine Kinase Like Expression Inhibits Gastric Cancer Cell Growth and Induces Apoptosis by Activation of ERK1/2 and Inactivation of NF-κB Signaling. | 2 |
| 33627787 | 2021 | Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers. | 18 |
| 34331012 | 2021 | MASTL regulates EGFR signaling to impact pancreatic cancer progression. | 6 |
| 32123010 | 2020 | AKT Regulates Mitotic Progression of Mammalian Cells by Phosphorylating MASTL, Leading to Protein Phosphatase 2A Inactivation. | 5 |
| 32311005 | 2020 | MASTL promotes cell contractility and motility through kinase-independent signaling. | 11 |
| 32692487 | 2020 | MASTL: A novel therapeutic target for Cancer Malignancy. | 13 |
| 32123010 | 2020 | AKT Regulates Mitotic Progression of Mammalian Cells by Phosphorylating MASTL, Leading to Protein Phosphatase 2A Inactivation. | 5 |
| 32311005 | 2020 | MASTL promotes cell contractility and motility through kinase-independent signaling. | 11 |
| 32692487 | 2020 | MASTL: A novel therapeutic target for Cancer Malignancy. | 13 |
| 30445205 | 2019 | Mitosis perturbation by MASTL depletion impairs the viability of thyroid tumor cells. | 10 |
Citation
Dessen P
MASTL (microtubule associated serine/threonine kinase like)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43356/mastl
