Identity
HGNC
LOCATION
10p13
LOCUSID
ALIAS
CNA43,DNA43,IMD80,PRO2249
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55388
MIM: 609357
HGNC: 18043
Ensembl: ENSG00000065328
Variants:
dbSNP: 55388
ClinVar: 55388
TCGA: ENSG00000065328
COSMIC: MCM10
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000065328 | ENST00000378694 | Q5T670 |
| ENSG00000065328 | ENST00000378714 | Q7L590 |
| ENSG00000065328 | ENST00000479669 | C9J600 |
| ENSG00000065328 | ENST00000484800 | Q7L590 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38262603 | 2024 | A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells. | 1 |
| 38262603 | 2024 | A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells. | 1 |
| 37848534 | 2023 | MCM10, a potential diagnostic, immunological, and prognostic biomarker in pan-cancer. | 0 |
| 37848534 | 2023 | MCM10, a potential diagnostic, immunological, and prognostic biomarker in pan-cancer. | 0 |
| 35394024 | 2022 | Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation. | 5 |
| 35813483 | 2022 | Over-Activation of Minichromosome Maintenance Protein 10 Promotes Genomic Instability in Early Stages of Breast Cancer. | 2 |
| 35394024 | 2022 | Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation. | 5 |
| 35813483 | 2022 | Over-Activation of Minichromosome Maintenance Protein 10 Promotes Genomic Instability in Early Stages of Breast Cancer. | 2 |
| 33340428 | 2021 | MCM10 compensates for Myc-induced DNA replication stress in breast cancer stem-like cells. | 17 |
| 33712616 | 2021 | Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening. | 17 |
| 34185429 | 2021 | Aberrant MCM10 SUMOylation induces genomic instability mediated by a genetic variant associated with survival of esophageal squamous cell carcinoma. | 7 |
| 34350781 | 2021 | Prognostic significance and function of MCM10 in human hepatocellular carcinoma. | 5 |
| 34645815 | 2021 | BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage. | 31 |
| 33340428 | 2021 | MCM10 compensates for Myc-induced DNA replication stress in breast cancer stem-like cells. | 17 |
| 33712616 | 2021 | Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening. | 17 |
Citation
Dessen P
MCM10 (minichromosome maintenance 10 replication initiation factor)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43357/mcm10
