PXK (PX domain containing serine/threonine kinase like)

2006-10-01  

Identity

HGNC
LOCATION
3p14.3
LOCUSID
ALIAS
MONAKA,SLOB
FUSION GENES

Other Information

Locus ID:

NCBI: 54899
MIM: 611450
HGNC: 23326
Ensembl: ENSG00000168297

Variants:

dbSNP: 54899
ClinVar: 54899
TCGA: ENSG00000168297
COSMIC: PXK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168297ENST00000302779W5RWE6
ENSG00000168297ENST00000356151Q7Z7A4
ENSG00000168297ENST00000383715H7BYG4
ENSG00000168297ENST00000383716Q7Z7A4
ENSG00000168297ENST00000459676U3KQS4
ENSG00000168297ENST00000463280E9PD56
ENSG00000168297ENST00000468776F8WAW8
ENSG00000168297ENST00000477308F8WDF7
ENSG00000168297ENST00000479134H7C4V0
ENSG00000168297ENST00000479241A0A0C4DG95
ENSG00000168297ENST00000484288Q7Z7A4
ENSG00000168297ENST00000491164C9IYJ2
ENSG00000168297ENST00000493474H7C529
ENSG00000168297ENST00000495557H7C4W2

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
339212542021Telomere Length and Male Fertility.12
339212542021Telomere Length and Male Fertility.12
245347572015PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6.14
255969072015Association between KIAA0319L, PXK and JAZF1 gene polymorphisms and unexplained recurrent pregnancy loss in Chinese Han couples.1
258521902015Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.15
245347572015PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6.14
255969072015Association between KIAA0319L, PXK and JAZF1 gene polymorphisms and unexplained recurrent pregnancy loss in Chinese Han couples.1
258521902015Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.15
237409372013A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.49
237409372013A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.49
212434902012Different genetic effect of PXK on systemic lupus erythematosus in the Korean population.2
225928612012Associations between PXK and TYK2 polymorphisms and systemic lupus erythematosus: a meta-analysis.9
212434902012Different genetic effect of PXK on systemic lupus erythematosus in the Korean population.2
225928612012Associations between PXK and TYK2 polymorphisms and systemic lupus erythematosus: a meta-analysis.9
208293102011Polymorphisms of PXK are associated with autoantibody production, but not disease risk, of systemic lupus erythematosus in Chinese mainland population.3

Citation

Dessen P

PXK (PX domain containing serine/threonine kinase like)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43440/pxk