Identity
HGNC
LOCATION
7q11.21
LOCUSID
ALIAS
RABEX5,RAP1,rabex-5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27342
MIM: 609700
HGNC: 17676
Ensembl: ENSG00000154710
Variants:
dbSNP: 27342
ClinVar: 27342
TCGA: ENSG00000154710
COSMIC: RABGEF1
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33166495 | 2021 | RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways. | 0 |
| 33166495 | 2021 | RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways. | 0 |
| 29360040 | 2018 | Endosomal Rab cycles regulate Parkin-mediated mitophagy. | 70 |
| 29360040 | 2018 | Endosomal Rab cycles regulate Parkin-mediated mitophagy. | 70 |
| 27791468 | 2017 | The STX6-VTI1B-VAMP3 complex facilitates xenophagy by regulating the fusion between recycling endosomes and autophagosomes. | 22 |
| 28617553 | 2017 | Higher RABEX-5 mRNA predicts unfavourable survival in patients with colorectal cancer. | 4 |
| 27791468 | 2017 | The STX6-VTI1B-VAMP3 complex facilitates xenophagy by regulating the fusion between recycling endosomes and autophagosomes. | 22 |
| 28617553 | 2017 | Higher RABEX-5 mRNA predicts unfavourable survival in patients with colorectal cancer. | 4 |
| 27601648 | 2016 | Rabex-5 is a lenalidomide target molecule that negatively regulates TLR-induced type 1 IFN production. | 8 |
| 27820702 | 2016 | Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. | 7 |
| 27601648 | 2016 | Rabex-5 is a lenalidomide target molecule that negatively regulates TLR-induced type 1 IFN production. | 8 |
| 27820702 | 2016 | Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. | 7 |
| 26002576 | 2015 | Elevated RABEX-5 protein expression predicts poor prognosis in combined small cell lung cancer. | 3 |
| 26430212 | 2015 | Rabaptin5 is recruited to endosomes by Rab4 and Rabex5 to regulate endosome maturation. | 20 |
| 26002576 | 2015 | Elevated RABEX-5 protein expression predicts poor prognosis in combined small cell lung cancer. | 3 |
Citation
Dessen P
RABGEF1 (RAB guanine nucleotide exchange factor 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43442/rabgef1
