RANBP3 (RAN binding protein 3)

2006-10-01  

Identity

HGNC
RANBP3
LOCATION
19p13.3
LOCUSID
8498
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8498
MIM: 603327
HGNC: 9850
Ensembl: ENSG00000031823

Variants:

dbSNP: 8498
ClinVar: 8498
TCGA: ENSG00000031823
COSMIC: RANBP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000031823ENST00000034275Q9H6Z4
ENSG00000031823ENST00000340578Q9H6Z4
ENSG00000031823ENST00000439268Q9H6Z4
ENSG00000031823ENST00000585339K7EQB8
ENSG00000031823ENST00000587263K7EPW1
ENSG00000031823ENST00000587463K7ENJ2
ENSG00000031823ENST00000587479K7EIJ4
ENSG00000031823ENST00000588010K7EID7
ENSG00000031823ENST00000589353K7ERD4
ENSG00000031823ENST00000590623K7EMH9
ENSG00000031823ENST00000591092B7Z7F3
ENSG00000031823ENST00000591333K7EMT3
ENSG00000031823ENST00000591736K7EN31
ENSG00000031823ENST00000592133K7EJ17
ENSG00000031823ENST00000592621K7ESQ0
ENSG00000031823ENST00000592771K7ENB9

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
HTLV-I infectionKEGGko05166
HTLV-I infectionKEGGhsa05166

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
318331102020Ran-binding protein 3 is associated with human spermatogenesis and male infertility.3
318331102020Ran-binding protein 3 is associated with human spermatogenesis and male infertility.3
287603392017Crystal structure of importin-α3 bound to the nuclear localization signal of Ran-binding protein 3.5
287603392017Crystal structure of importin-α3 bound to the nuclear localization signal of Ran-binding protein 3.5
267634462016RanBP3 Regulates Melanoma Cell Proliferation via Selective Control of Nuclear Export.3
267634462016RanBP3 Regulates Melanoma Cell Proliferation via Selective Control of Nuclear Export.3
233038292013The role of Ran-binding protein 3 during influenza A virus replication.10
233038292013The role of Ran-binding protein 3 during influenza A virus replication.10
213649252011Insights into the function of the CRM1 cofactor RanBP3 from the structure of its Ran-binding domain.10
213649252011Insights into the function of the CRM1 cofactor RanBP3 from the structure of its Ran-binding domain.10
192890812009Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-beta signaling.60
192890812009Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-beta signaling.60
182802412008Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transport.50
182802412008Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transport.50
146124152003A multifunctional domain in human CRM1 (exportin 1) mediates RanBP3 binding and multimerization of human T-cell leukemia virus type 1 Rex protein.20

Citation

Dessen P

RANBP3 (RAN binding protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43444/favicon/haematological-explorer/