RHEBL1 (RHEB like 1)

2006-10-01 Affiliation

Identity

HGNC

RHEBL1

LOCATION

12q13.12

LOCUSID

121268

ALIAS

RHEBL1c

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 121268
HGNC: 21166
Ensembl: ENSG00000167550

Variants:

dbSNP: 121268
ClinVar: 121268
TCGA: ENSG00000167550
COSMIC: RHEBL1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000167550	ENST00000301068	Q8TAI7
ENSG00000167550	ENST00000420065	C9JQQ1
ENSG00000167550	ENST00000550675	F8W1T5
ENSG00000167550	ENST00000550797	Q8TAI7

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
34375645	2021	Rheb1 promotes glucose-stimulated insulin secretion in human and mouse β-cells by upregulating GLUT expression.	5
34375645	2021	Rheb1 promotes glucose-stimulated insulin secretion in human and mouse β-cells by upregulating GLUT expression.	5
28209923	2017	Novel involvement of RhebL1 in sphingosylphosphorylcholine-induced keratin phosphorylation and reorganization: Binding to and activation of AKT1.	6
28209923	2017	Novel involvement of RhebL1 in sphingosylphosphorylcholine-induced keratin phosphorylation and reorganization: Binding to and activation of AKT1.	6
25422319	2015	Rheb protein binds CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase, and dihydroorotase) protein in a GTP- and effector domain-dependent manner and influences its cellular localization and carbamoyl-phosphate synthetase (CPSase) activity.	15
25422319	2015	Rheb protein binds CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase, and dihydroorotase) protein in a GTP- and effector domain-dependent manner and influences its cellular localization and carbamoyl-phosphate synthetase (CPSase) activity.	15
24127550	2013	DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia.	14
24127550	2013	DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia.	14
21655954	2012	Effects of RhebL1 silencing on the mTOR pathway.	7
21655954	2012	Effects of RhebL1 silencing on the mTOR pathway.	7
16098514	2005	Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1.	48
16328882	2005	Identification and characterization of RHEBL1, a novel member of Ras family, which activates transcriptional activities of NF-kappa B.	12
16098514	2005	Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1.	48
16328882	2005	Identification and characterization of RHEBL1, a novel member of Ras family, which activates transcriptional activities of NF-kappa B.	12

Citation

Dessen P

RHEBL1 (RHEB like 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43465/gene-fusions-explorer/haematological-explorer/css/lib/dataTables.bootstrap.min.css