Identity
HGNC
LOCATION
16p12.3
LOCUSID
ALIAS
61E3.4,ATX,LIP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23049
MIM: 607032
HGNC: 30045
Ensembl: ENSG00000157106
Variants:
dbSNP: 23049
ClinVar: 23049
TCGA: ENSG00000157106
COSMIC: SMG1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36400430 | 2023 | SMG1, a nonsense-mediated mRNA decay (NMD) regulator, as a candidate therapeutic target in multiple myeloma. | 1 |
| 36400430 | 2023 | SMG1, a nonsense-mediated mRNA decay (NMD) regulator, as a candidate therapeutic target in multiple myeloma. | 1 |
| 34761935 | 2021 | SMG1 and CDK12 Link ΔNp63α Phosphorylation to RNA Surveillance in Keratinocytes. | 3 |
| 34842356 | 2021 | Large-scale genomic sequencing reveals adaptive opportunity of targeting mutated-PI3Kα in early and advanced HER2-positive breast cancer. | 6 |
| 34761935 | 2021 | SMG1 and CDK12 Link ΔNp63α Phosphorylation to RNA Surveillance in Keratinocytes. | 3 |
| 34842356 | 2021 | Large-scale genomic sequencing reveals adaptive opportunity of targeting mutated-PI3Kα in early and advanced HER2-positive breast cancer. | 6 |
| 32469312 | 2020 | Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity. | 16 |
| 32469312 | 2020 | Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity. | 16 |
| 31469826 | 2019 | A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene. | 8 |
| 31659158 | 2019 | MicroRNA-18a promotes cancer progression through SMG1 suppression and mTOR pathway activation in nasopharyngeal carcinoma. | 22 |
| 31729466 | 2019 | Cryo-EM structure of SMG1-SMG8-SMG9 complex. | 13 |
| 31792449 | 2019 | InsP(6) binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex. | 20 |
| 31469826 | 2019 | A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene. | 8 |
| 31659158 | 2019 | MicroRNA-18a promotes cancer progression through SMG1 suppression and mTOR pathway activation in nasopharyngeal carcinoma. | 22 |
| 31729466 | 2019 | Cryo-EM structure of SMG1-SMG8-SMG9 complex. | 13 |
Citation
Dessen P
SMG1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43495/smg1
