Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6732
MIM: 601939
HGNC: 11305
Ensembl: ENSG00000096063
Variants:
dbSNP: 6732
ClinVar: 6732
TCGA: ENSG00000096063
COSMIC: SRPK1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Herpes simplex infection | KEGG | ko05168 |
| Herpes simplex infection | KEGG | hsa05168 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38376036 | 2024 | Spatiotemporal expression and coexpression patterns of SRPK1 in the human brain: A neurodevelopmental perspective. | 0 |
| 38376036 | 2024 | Spatiotemporal expression and coexpression patterns of SRPK1 in the human brain: A neurodevelopmental perspective. | 0 |
| 36226860 | 2023 | SRPK1 promotes sepsis-induced acute lung injury via regulating PI3K/AKT/FOXO3 signaling. | 2 |
| 36869126 | 2023 | Serine-arginine protein kinase 1 (SRPK1) promotes EGFR-TKI resistance by enhancing GSK3β Ser9 autophosphorylation independent of its kinase activity in non-small-cell lung cancer. | 6 |
| 36226860 | 2023 | SRPK1 promotes sepsis-induced acute lung injury via regulating PI3K/AKT/FOXO3 signaling. | 2 |
| 36869126 | 2023 | Serine-arginine protein kinase 1 (SRPK1) promotes EGFR-TKI resistance by enhancing GSK3β Ser9 autophosphorylation independent of its kinase activity in non-small-cell lung cancer. | 6 |
| 34964567 | 2022 | SRPK1 promotes cell proliferation and tumor growth of osteosarcoma through activation of the NF-κB signaling pathway. | 0 |
| 35192432 | 2022 | Increased expression of SRPK1 (serine/arginine-rich protein-specific kinase 1) is associated with progression and unfavorable prognosis in cervical squamous cell carcinoma. | 4 |
| 36303126 | 2022 | Inhibition of SRPK1, a key splicing regulator, exhibits antitumor and chemotherapeutic-sensitizing effects on extranodal NK/T-cell lymphoma cells. | 1 |
| 34964567 | 2022 | SRPK1 promotes cell proliferation and tumor growth of osteosarcoma through activation of the NF-κB signaling pathway. | 0 |
| 35192432 | 2022 | Increased expression of SRPK1 (serine/arginine-rich protein-specific kinase 1) is associated with progression and unfavorable prognosis in cervical squamous cell carcinoma. | 4 |
| 36303126 | 2022 | Inhibition of SRPK1, a key splicing regulator, exhibits antitumor and chemotherapeutic-sensitizing effects on extranodal NK/T-cell lymphoma cells. | 1 |
| 32359191 | 2021 | A conserved sequence motif bridges two protein kinases for enhanced phosphorylation and nuclear function of a splicing factor. | 6 |
| 33602301 | 2021 | SRPK1/2 and PP1α exert opposite functions by modulating SRSF1-guided MKNK2 alternative splicing in colon adenocarcinoma. | 31 |
| 33722639 | 2021 | A HIF1A/miR-485-5p/SRPK1 axis modulates the aggressiveness of glioma cells upon hypoxia. | 7 |
Citation
Dessen P
SRPK1 (SRSF protein kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43505/srpk1
