TAF1 (TATA-box binding protein associated factor 1)

2006-10-01  

Identity

HGNC
TAF1
LOCATION
Xq13.1
LOCUSID
6872
ALIAS
BA2R,CCG1,CCGS,DYT3,DYT3/TAF1,KAT4,MRXS33,N-TAF1,NSCL2,OF,P250,TAF(II)250,TAF2A,TAFII-250,TAFII250,XDP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6872
MIM: 313650
HGNC: 11535
Ensembl: ENSG00000147133

Variants:

dbSNP: 6872
ClinVar: 6872
TCGA: ENSG00000147133
COSMIC: TAF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147133ENST00000276072P21675
ENSG00000147133ENST00000373775H7BY98
ENSG00000147133ENST00000373790P21675
ENSG00000147133ENST00000423759P21675
ENSG00000147133ENST00000437147H7C2K9
ENSG00000147133ENST00000463163H0Y8N6
ENSG00000147133ENST00000483985H0Y9L7

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Basal transcription factorsKEGGko03022
Basal transcription factorsKEGGhsa03022
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
HIV Life CycleREACTOMER-HSA-162587
Late Phase of HIV Life CycleREACTOMER-HSA-162599
Transcription of the HIV genomeREACTOMER-HSA-167172
HIV Transcription InitiationREACTOMER-HSA-167161
RNA Polymerase II HIV Promoter EscapeREACTOMER-HSA-167162
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Pre-transcription EventsREACTOMER-HSA-674695
RNA Polymerase II Transcription Pre-Initiation And Promoter OpeningREACTOMER-HSA-73779
RNA Polymerase II Transcription Initiation And Promoter ClearanceREACTOMER-HSA-76042
RNA Polymerase II Transcription InitiationREACTOMER-HSA-75953
RNA Polymerase II Promoter EscapeREACTOMER-HSA-73776
Regulation of TP53 ActivityREACTOMER-HSA-5633007
Regulation of TP53 Activity through PhosphorylationREACTOMER-HSA-6804756

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
369587112023TAF1 bromodomain inhibition as a candidate epigenetic driver of congenital heart disease.0
371323942023MIAT shuttled by tumor-secreted exosomes promotes paclitaxel resistance in esophageal cancer cells by activating the TAF1/SREBF1 axis.0
373862152023Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID.4
369587112023TAF1 bromodomain inhibition as a candidate epigenetic driver of congenital heart disease.0
371323942023MIAT shuttled by tumor-secreted exosomes promotes paclitaxel resistance in esophageal cancer cells by activating the TAF1/SREBF1 axis.0
373862152023Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID.4
350524662022Elucidating Hexanucleotide Repeat Number and Methylation within the X-Linked Dystonia-Parkinsonism (XDP)-Related SVA Retrotransposon in TAF1 with Nanopore Sequencing.5
359477452022Differential dependencies of human RNA polymerase II promoters on TBP, TAF1, TFIIB and XPB.14
363681532022TAF1 promotes NSCLC cell epithelial-mesenchymal transition by transcriptionally activating TGFβ1.2
350524662022Elucidating Hexanucleotide Repeat Number and Methylation within the X-Linked Dystonia-Parkinsonism (XDP)-Related SVA Retrotransposon in TAF1 with Nanopore Sequencing.5
359477452022Differential dependencies of human RNA polymerase II promoters on TBP, TAF1, TFIIB and XPB.14
363681532022TAF1 promotes NSCLC cell epithelial-mesenchymal transition by transcriptionally activating TGFβ1.2
329753182021TAF1 Transcripts and Neurofilament Light Chain as Biomarkers for X-linked Dystonia-Parkinsonism.11
340568632021Yeast Bromodomain Factor 1 and Its Human Homolog TAF1 Play Conserved Roles in Promoting Homologous Recombination.8
344894962021Template activating factor-I epigenetically regulates the TERT transcription in human cancer cells.1

Citation

Dessen P

TAF1 (TATA-box binding protein associated factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43523/taf1