Identity
HGNC
LOCATION
12q24.23
LOCUSID
ALIAS
DPK,JIK,MAP3K18,hKFC-A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51347
MIM: 616711
HGNC: 18133
Ensembl: ENSG00000135090
Variants:
dbSNP: 51347
ClinVar: 51347
TCGA: ENSG00000135090
COSMIC: TAOK3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA445208 | Pain | Disease | ClinicalAnnotation | associated | PD | 30031856 | |
| PA445210 | Pain, Postoperative | Disease | ClinicalAnnotation | associated | PD | ||
| PA450550 | morphine | Chemical | ClinicalAnnotation | associated | PD | ||
| PA452618 | opioids | Chemical | ClinicalAnnotation | associated | PD | 30031856 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38166031 | 2024 | The induction of SHP-1 degradation by TAOK3 ensures the responsiveness of T cells to TCR stimulation. | 2 |
| 38166031 | 2024 | The induction of SHP-1 degradation by TAOK3 ensures the responsiveness of T cells to TCR stimulation. | 2 |
| 37705061 | 2023 | TAOK3 Facilitates Esophageal Squamous Cell Carcinoma Progression and Cisplatin Resistance Through Augmenting Autophagy Mediated by IRGM. | 1 |
| 37705061 | 2023 | TAOK3 Facilitates Esophageal Squamous Cell Carcinoma Progression and Cisplatin Resistance Through Augmenting Autophagy Mediated by IRGM. | 1 |
| 34506849 | 2022 | The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice. | 3 |
| 34506849 | 2022 | The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice. | 3 |
| 33414172 | 2021 | Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5α Promotes Cancer Invasion and Tumor Growth. | 7 |
| 34634521 | 2021 | STE20-type kinase TAOK3 regulates hepatic lipid partitioning. | 10 |
| 33414172 | 2021 | Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5α Promotes Cancer Invasion and Tumor Growth. | 7 |
| 34634521 | 2021 | STE20-type kinase TAOK3 regulates hepatic lipid partitioning. | 10 |
| 32807497 | 2020 | TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization. | 10 |
| 33087151 | 2020 | Kinase shRNA screening reveals that TAOK3 enhances microtubule-targeted drug resistance of breast cancer cells via the NF-κB signaling pathway. | 12 |
| 32807497 | 2020 | TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization. | 10 |
| 33087151 | 2020 | Kinase shRNA screening reveals that TAOK3 enhances microtubule-targeted drug resistance of breast cancer cells via the NF-κB signaling pathway. | 12 |
| 30031856 | 2018 | Single-Nucleotide Polymorphisms in TAOK3 Are Associated With High Opioid Requirement for Pain Management in Patients With Advanced Cancer Admitted to a Tertiary Palliative Care Unit. | 5 |
Citation
Dessen P
TAOK3 (TAO kinase 3)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43526/taok3
