TRAF3IP1 (TRAF3 interacting protein 1)

2006-10-01  

Identity

HGNC
TRAF3IP1
LOCATION
2q37.3
LOCUSID
26146
ALIAS
FAP116,IFT54,MIP-T3,MIPT3,SLSN9
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 26146
MIM: 607380
HGNC: 17861
Ensembl: ENSG00000204104

Variants:

dbSNP: 26146
ClinVar: 26146
TCGA: ENSG00000204104
COSMIC: TRAF3IP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204104ENST00000373327Q8TDR0
ENSG00000204104ENST00000391993Q8TDR0
ENSG00000204104ENST00000409739H7BZ10

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Cilium AssemblyREACTOMER-HSA-5617833
Intraflagellar transportREACTOMER-HSA-5620924

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
385517982024(1)H, (13)C, and (15)N resonance assignments and solution structure of the N-terminal divergent calponin homology (NN-CH) domain of human intraflagellar transport protein 54.0
385517982024(1)H, (13)C, and (15)N resonance assignments and solution structure of the N-terminal divergent calponin homology (NN-CH) domain of human intraflagellar transport protein 54.0
264872682015Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization.58
264872682015Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization.58
215109432011The C-terminus of MIP-T3 protein is required for ubiquitin-proteasome-mediated degradation in human cells.1
220799892011MIP-T3 is a negative regulator of innate type I IFN response.26
215109432011The C-terminus of MIP-T3 protein is required for ubiquitin-proteasome-mediated degradation in human cells.1
220799892011MIP-T3 is a negative regulator of innate type I IFN response.26
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203915332010Proteomic analysis reveals novel binding partners of MIP-T3 in human cells.7
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203915332010Proteomic analysis reveals novel binding partners of MIP-T3 in human cells.7
192512512009Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses.31
198984822009Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.105
192512512009Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses.31

Citation

Dessen P

TRAF3IP1 (TRAF3 interacting protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43538/teaching-explorer/haematological-explorer/favicon/apple-touch-icon.png