RGS13 (regulator of G protein signaling 13)

2007-02-01 Affiliation

Identity

HGNC

RGS13

LOCATION

1q31.2

LOCUSID

6003

ALIAS

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 6003
MIM: 607190
HGNC: 9995
Ensembl: ENSG00000127074

Variants:

dbSNP: 6003
ClinVar: 6003
TCGA: ENSG00000127074
COSMIC: RGS13

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000127074	ENST00000391995	O14921
ENSG00000127074	ENST00000391995	A0A024R989
ENSG00000127074	ENST00000543215	O14921
ENSG00000127074	ENST00000543215	A0A024R989

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Signal Transduction	REACTOME	R-HSA-162582
Signaling by GPCR	REACTOME	R-HSA-372790
GPCR downstream signaling	REACTOME	R-HSA-388396
G alpha (i) signalling events	REACTOME	R-HSA-418594

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
30308012	2018	MicroRNA and mRNA expression associated with ectopic germinal centers in thymus of myasthenia gravis.	14
30308012	2018	MicroRNA and mRNA expression associated with ectopic germinal centers in thymus of myasthenia gravis.	14
21531726	2011	p53 negatively regulates RGS13 protein expression in immune cells.	5
21531726	2011	p53 negatively regulates RGS13 protein expression in immune cells.	5
20468064	2010	Association study of 182 candidate genes in anorexia nervosa.	32
20627871	2010	Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.	7
20974683	2010	Phosphorylation of RGS13 by the cyclic AMP-dependent protein kinase inhibits RGS13 degradation.	10
20468064	2010	Association study of 182 candidate genes in anorexia nervosa.	32
20627871	2010	Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.	7
20974683	2010	Phosphorylation of RGS13 by the cyclic AMP-dependent protein kinase inhibits RGS13 degradation.	10
19017978	2008	RGS13 controls g protein-coupled receptor-evoked responses of human mast cells.	25
19017978	2008	RGS13 controls g protein-coupled receptor-evoked responses of human mast cells.	25
16565322	2006	RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization.	34
16565322	2006	RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization.	34
12970790	2003	High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma.	32

Citation

Dessen P

RGS13 (regulator of G protein signaling 13)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43608