EGFL8 (EGF like domain multiple 8)

2011-10-01  

Identity

HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
C6orf8,NG3
FUSION GENES

Other Information

Locus ID:

NCBI: 80864
MIM: 609897
HGNC: 13944
Ensembl: ENSG00000241404

Variants:

dbSNP: 80864
ClinVar: 80864
TCGA: ENSG00000241404
COSMIC: EGFL8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000241404ENST00000333845Q99944
ENSG00000241404ENST00000333845A0A1U9X7N9
ENSG00000241404ENST00000395512Q99944
ENSG00000241404ENST00000395512A0A1U9X7N9
ENSG00000241404ENST00000432129Q5JP22

Expression (GTEx)

0
100
200
300
400
500
600

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
337126102021Schwann cell plasticity regulates neuroblastic tumor cell differentiation via epidermal growth factor-like protein 8.30
341306592021Down-regulation of EGFL8 regulates migration, invasion and apoptosis of hepatocellular carcinoma through activating Notch signaling pathway.5
346261762021Whole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensities.17
337126102021Schwann cell plasticity regulates neuroblastic tumor cell differentiation via epidermal growth factor-like protein 8.30
341306592021Down-regulation of EGFL8 regulates migration, invasion and apoptosis of hepatocellular carcinoma through activating Notch signaling pathway.5
346261762021Whole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensities.17
217376482011Down-regulation of EGFL8: a novel prognostic biomarker for patients with colorectal cancer.4
219657492011Down-regulation of EGFL8: a novel biomarker for advanced gastric cancer.6
217376482011Down-regulation of EGFL8: a novel prognostic biomarker for patients with colorectal cancer.4
219657492011Down-regulation of EGFL8: a novel biomarker for advanced gastric cancer.6
205876102010Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.3
205876102010Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.3
191438142009Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1.20
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.58
191438142009Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1.20

Citation

Dessen P

EGFL8 (EGF like domain multiple 8)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/43611/deep-insight-explorer/favicon/js/lib/bootstrap.min.js