Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55312
MIM: 613010
HGNC: 30324
Ensembl: ENSG00000135002
Variants:
dbSNP: 55312
ClinVar: 55312
TCGA: ENSG00000135002
COSMIC: RFK
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000135002 | ENST00000376736 | Q969G6 |
| ENSG00000135002 | ENST00000490113 | H7C4G0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10074 | escitalopram | Chemical | ClinicalAnnotation | associated | PD | ||
| PA447207 | Depressive Disorder | Disease | ClinicalAnnotation | associated | PD | ||
| PA449015 | citalopram | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 26288249 | 2015 | Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development. | 25 |
| 26288249 | 2015 | Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development. | 25 |
| 22158615 | 2012 | Death receptors 4 and 5 activate Nox1 NADPH oxidase through riboflavin kinase to induce reactive oxygen species-mediated apoptotic cell death. | 14 |
| 22158615 | 2012 | Death receptors 4 and 5 activate Nox1 NADPH oxidase through riboflavin kinase to induce reactive oxygen species-mediated apoptotic cell death. | 14 |
| 21308351 | 2011 | Involvement of riboflavin kinase expression in cellular sensitivity against cisplatin. | 13 |
| 21308351 | 2011 | Involvement of riboflavin kinase expression in cellular sensitivity against cisplatin. | 13 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 19641494 | 2009 | Riboflavin kinase couples TNF receptor 1 to NADPH oxidase. | 91 |
| 19641494 | 2009 | Riboflavin kinase couples TNF receptor 1 to NADPH oxidase. | 91 |
| 14580199 | 2003 | Ligand binding-induced conformational changes in riboflavin kinase: structural basis for the ordered mechanism. | 18 |
| 14580199 | 2003 | Ligand binding-induced conformational changes in riboflavin kinase: structural basis for the ordered mechanism. | 18 |
Citation
Dessen P
RFK (riboflavin kinase)
Atlas Genet Cytogenet Oncol Haematol. 2012-03-01
Online version: http://atlasgeneticsoncology.org/gene/43617/rfk
