Identity
HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
HLA-DNA,HLA-DZA,HLADZ
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3111
MIM: 142930
HGNC: 4936
Ensembl: ENSG00000204252
Variants:
dbSNP: 3111
ClinVar: 3111
TCGA: ENSG00000204252
COSMIC: HLA-DOA
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 27486778 | 2016 | Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis. | 30 |
| 27486778 | 2016 | Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis. | 30 |
| 25758996 | 2015 | Genome-wide association analysis on five isolated populations identifies variants of the HLA-DOA gene associated with white wine liking. | 2 |
| 25874709 | 2015 | Association of polymorphisms in HLA antigen presentation-related genes with the outcomes of HCV infection. | 8 |
| 26610428 | 2015 | pH-susceptibility of HLA-DO tunes DO/DM ratios to regulate HLA-DM catalytic activity. | 15 |
| 25758996 | 2015 | Genome-wide association analysis on five isolated populations identifies variants of the HLA-DOA gene associated with white wine liking. | 2 |
| 25874709 | 2015 | Association of polymorphisms in HLA antigen presentation-related genes with the outcomes of HCV infection. | 8 |
| 26610428 | 2015 | pH-susceptibility of HLA-DO tunes DO/DM ratios to regulate HLA-DM catalytic activity. | 15 |
| 24384427 | 2014 | Genome-wide study reveals an important role of spontaneous autoimmunity, cardiomyocyte differentiation defect and anti-angiogenic activities in gender-specific gene expression in Keshan disease. | 5 |
| 24530695 | 2014 | Human leukocyte antigen-DO regulates surface presentation of human leukocyte antigen class II-restricted antigens on B cell malignancies. | 6 |
| 24384427 | 2014 | Genome-wide study reveals an important role of spontaneous autoimmunity, cardiomyocyte differentiation defect and anti-angiogenic activities in gender-specific gene expression in Keshan disease. | 5 |
| 24530695 | 2014 | Human leukocyte antigen-DO regulates surface presentation of human leukocyte antigen class II-restricted antigens on B cell malignancies. | 6 |
| 23222639 | 2013 | HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism. | 71 |
| 23222639 | 2013 | HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism. | 71 |
| 22733780 | 2012 | Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis. | 28 |
Citation
Dessen P
HLA-DOA (major histocompatibility complex, class II, DO alpha)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43624/hla-doa
