Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4353
MIM: 606989
HGNC: 7218
Ensembl: ENSG00000005381
Variants:
dbSNP: 4353
ClinVar: 4353
TCGA: ENSG00000005381
COSMIC: MPO
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000005381 | ENST00000225275 | P05164 |
| ENSG00000005381 | ENST00000577220 | J3QSF7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443297 | Agranulocytosis | Disease | VariantAnnotation | not associated | PD | 27168101 | |
| PA445113 | Neutropenia | Disease | VariantAnnotation | not associated | PD | 27168101 | |
| PA449061 | clozapine | Chemical | VariantAnnotation | not associated | PD | 27168101 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35420291 | 2024 | The effect of fetal hypoxia on myeloperoxidase levels in cord blood: a prospective study. | 0 |
| 38164522 | 2024 | Treatment regimens and disease activity could alter salivary myeloperoxidase levels in patients with inflammatory bowel diseases. | 1 |
| 38563171 | 2024 | [The auxiliary diagnostic value of ECP and MPO expression in nasal secretions in different types of rhinitis]. | 0 |
| 35420291 | 2024 | The effect of fetal hypoxia on myeloperoxidase levels in cord blood: a prospective study. | 0 |
| 38164522 | 2024 | Treatment regimens and disease activity could alter salivary myeloperoxidase levels in patients with inflammatory bowel diseases. | 1 |
| 38563171 | 2024 | [The auxiliary diagnostic value of ECP and MPO expression in nasal secretions in different types of rhinitis]. | 0 |
| 36325594 | 2023 | Adult mixed phenotype acute leukemia (MPAL): B/myeloid MPAL(isoMPO) is distinct from other MPAL subtypes. | 1 |
| 36730508 | 2023 | Paediatric-onset generalized pustular psoriasis secondary to myeloperoxidase mutations. | 0 |
| 37058998 | 2023 | NOX4 as a critical effector mediating neuroinflammatory cytokines, myeloperoxidase and osteopontin, specifically in astrocytes in the hippocampus in Parkinson's disease. | 6 |
| 37280612 | 2023 | Atrial epicardial adipose tissue abundantly secretes myeloperoxidase and activates atrial fibroblasts in patients with atrial fibrillation. | 2 |
| 37288959 | 2023 | Relationship between disease severity and myeloperoxidase in chronic viral hepatitis: a prospective study. | 1 |
| 37569455 | 2023 | Salivary Alterations of Myeloperoxidase in Patients with Systemic Diseases: A Systematic Review. | 1 |
| 37656254 | 2023 | Myeloperoxidase is a critical mediator of anthracycline-induced cardiomyopathy. | 2 |
| 37776707 | 2023 | Myeloperoxidase enhances the migration and invasion of human choriocarcinoma JEG-3 cells. | 0 |
| 37982229 | 2023 | Monomeric myeloperoxidase is a specific biomarker for early-stage ovarian cancer. | 0 |
Citation
Dessen P
MPO (myeloperoxidase)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43627/mpo
