SYP (synaptophysin)

2007-02-01  

Identity

HGNC
SYP
LOCATION
Xp11.23
LOCUSID
6855
ALIAS
MRX96,MRXSYP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6855
MIM: 313475
HGNC: 11506
Ensembl: ENSG00000102003

Variants:

dbSNP: 6855
ClinVar: 6855
TCGA: ENSG00000102003
COSMIC: SYP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102003ENST00000263233P08247
ENSG00000102003ENST00000376303G5E9A2
ENSG00000102003ENST00000466635F2Z3E1
ENSG00000102003ENST00000469389F2Z3E1
ENSG00000102003ENST00000472598H7C4W3
ENSG00000102003ENST00000479808P08247

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
371337252023Association between genetic polymorphisms of synaptophysin (SYP) gene and attention deficit hyperactivity disorder in Korean subjects.0
371337252023Association between genetic polymorphisms of synaptophysin (SYP) gene and attention deficit hyperactivity disorder in Korean subjects.0
343100402022Slowly progressive behavioral frontotemporal dementia syndrome in a family co-segregating the C9orf72 expansion and a Synaptophysin mutation.1
364012842022Aberrant synaptophysin expression in classic Hodgkin lymphoma.0
343100402022Slowly progressive behavioral frontotemporal dementia syndrome in a family co-segregating the C9orf72 expansion and a Synaptophysin mutation.1
364012842022Aberrant synaptophysin expression in classic Hodgkin lymphoma.0
334852912021Significance of chromogranin A and synaptophysin in medullary thyroid carcinoma.1
336074782021Synaptophysin expression in (V600EBRAF-)mutated advanced colorectal cancers identifies a new subgroup of tumours with worse prognosis.4
337297402021Clinicopathologic Characterization of Epithelioid Hemangioendothelioma in a Series of 62 Cases: A Proposal of Risk Stratification and Identification of a Synaptophysin-positive Aggressive Subset.12
343206912021The prognostic significance of neuroendocrine markers and somatostatin receptor 2 in hepatocellular carcinoma.1
334852912021Significance of chromogranin A and synaptophysin in medullary thyroid carcinoma.1
336074782021Synaptophysin expression in (V600EBRAF-)mutated advanced colorectal cancers identifies a new subgroup of tumours with worse prognosis.4
337297402021Clinicopathologic Characterization of Epithelioid Hemangioendothelioma in a Series of 62 Cases: A Proposal of Risk Stratification and Identification of a Synaptophysin-positive Aggressive Subset.12
343206912021The prognostic significance of neuroendocrine markers and somatostatin receptor 2 in hepatocellular carcinoma.1
305853812020Oxytocin inhibits methamphetamine-associated learning and memory alterations by regulating DNA methylation at the Synaptophysin promoter.8

Citation

Dessen P

SYP (synaptophysin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43634