SPN (sialophorin)

2007-02-01  

Identity

HGNC
SPN
LOCATION
16p11.2
LOCUSID
6693
ALIAS
CD43,GALGP,GPL115,LSN

Other Information

Locus ID:

NCBI: 6693
MIM: 182160
HGNC: 11249
Ensembl: ENSG00000197471

Variants:

dbSNP: 6693
ClinVar: 6693
TCGA: ENSG00000197471
COSMIC: SPN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197471ENST00000360121P16150
ENSG00000197471ENST00000360121A0A024R629
ENSG00000197471ENST00000395389P16150
ENSG00000197471ENST00000395389A0A024R629
ENSG00000197471ENST00000436527C9JUK7
ENSG00000197471ENST00000563039P16150
ENSG00000197471ENST00000563039A0A024R629
ENSG00000197471ENST00000652691P16150
ENSG00000197471ENST00000652691A0A024R629

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Cell adhesion molecules (CAMs)KEGGhsa04514
Epstein-Barr virus infectionKEGGhsa05169
Epstein-Barr virus infectionKEGGko05169
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733
Basigin interactionsREACTOMER-HSA-210991

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
332499402021CD43 in the malignant flow cytometry laboratory in 2020.0
335330432021CD43 (sialophorin) is involved in the induction of extracellular matrix remodeling and angiogenesis by lung cancer cells.0
336404572021Identification and functional characterization of a Siglec-7 counter-receptor on K562 cells.17
332499402021CD43 in the malignant flow cytometry laboratory in 2020.0
335330432021CD43 (sialophorin) is involved in the induction of extracellular matrix remodeling and angiogenesis by lung cancer cells.0
336404572021Identification and functional characterization of a Siglec-7 counter-receptor on K562 cells.17
321933432020Virion-incorporated PSGL-1 and CD43 inhibit both cell-free infection and transinfection of HIV-1 by preventing virus-cell binding.14
327166062020Determination of CD43 and CD200 surface expression improves accuracy of B-cell lymphoma immunophenotyping.9
321933432020Virion-incorporated PSGL-1 and CD43 inhibit both cell-free infection and transinfection of HIV-1 by preventing virus-cell binding.14
327166062020Determination of CD43 and CD200 surface expression improves accuracy of B-cell lymphoma immunophenotyping.9
306907342019Sialomucin CD43 regulates T helper type 17 cell intercellular adhesion molecule 1 dependent adhesion, apical migration and transendothelial migration.9
311579552019CD43 and CD49d from the B-Cell Chronic Lymphoproliferative Disorders Diagnostic Panel Are Useful to Detect Erythroid Dysplasia.1
306907342019Sialomucin CD43 regulates T helper type 17 cell intercellular adhesion molecule 1 dependent adhesion, apical migration and transendothelial migration.9
311579552019CD43 and CD49d from the B-Cell Chronic Lymphoproliferative Disorders Diagnostic Panel Are Useful to Detect Erythroid Dysplasia.1
280731732018Expression of CD43 in chronic lymphoproliferative leukemias.10

Citation

Dessen P

SPN (sialophorin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43678