Identity
HGNC
LOCATION
9q21.2
LOCUSID
ALIAS
BMCC1,BNIPXL,C9orf65,KIAA0367
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 158471
MIM: 610691
HGNC: 25209
Ensembl: ENSG00000106772
Variants:
dbSNP: 158471
ClinVar: 158471
TCGA: ENSG00000106772
COSMIC: PRUNE2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36564567 | 2023 | Exome sequencing of affected duos and trios uncovers PRUNE2 as a novel prostate cancer predisposition gene. | 2 |
| 36564567 | 2023 | Exome sequencing of affected duos and trios uncovers PRUNE2 as a novel prostate cancer predisposition gene. | 2 |
| 35929169 | 2022 | FOXF2 Regulates PRUNE2 Transcription in the Pathogenesis of Colorectal Cancer. | 3 |
| 35929169 | 2022 | FOXF2 Regulates PRUNE2 Transcription in the Pathogenesis of Colorectal Cancer. | 3 |
| 31170959 | 2019 | Programmed expression of pro-apoptotic BMCC1 during apoptosis, triggered by DNA damage in neuroblastoma cells. | 5 |
| 31170959 | 2019 | Programmed expression of pro-apoptotic BMCC1 during apoptosis, triggered by DNA damage in neuroblastoma cells. | 5 |
| 27453342 | 2016 | Transcriptional regulation of BMCC1 mediated by E2F1 in neuroblastoma cells. | 2 |
| 27453342 | 2016 | Transcriptional regulation of BMCC1 mediated by E2F1 in neuroblastoma cells. | 2 |
| 25387265 | 2015 | Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion. | 40 |
| 25611382 | 2015 | BMCC1, which is an interacting partner of BCL2, attenuates AKT activity, accompanied by apoptosis. | 9 |
| 26080435 | 2015 | PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3. | 118 |
| 25387265 | 2015 | Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion. | 40 |
| 25611382 | 2015 | BMCC1, which is an interacting partner of BCL2, attenuates AKT activity, accompanied by apoptosis. | 9 |
| 26080435 | 2015 | PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3. | 118 |
| 24040105 | 2013 | BMCC1 is an AP-2 associated endosomal protein in prostate cancer cells. | 7 |
Citation
Dessen P
PRUNE2 (prune homolog 2 with BCH domain)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43690/prune2
