Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10733
MIM: 605031
HGNC: 11397
Ensembl: ENSG00000142731
Variants:
dbSNP: 10733
ClinVar: 10733
TCGA: ENSG00000142731
COSMIC: PLK4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38290657 | 2024 | Polo-like kinase 4 promotes tumorigenesis and glucose metabolism in glioma by activating AKT1 signaling. | 0 |
| 38490717 | 2024 | CRL4(DCAF1) ubiquitin ligase regulates PLK4 protein levels to prevent premature centriole duplication. | 0 |
| 38290657 | 2024 | Polo-like kinase 4 promotes tumorigenesis and glucose metabolism in glioma by activating AKT1 signaling. | 0 |
| 38490717 | 2024 | CRL4(DCAF1) ubiquitin ligase regulates PLK4 protein levels to prevent premature centriole duplication. | 0 |
| 35973104 | 2023 | Polo-like Kinase 4: the Variation During Therapy and its Relation to Treatment Response and Prognostic Risk Stratification in Childhood Acute Lymphoblastic Leukemia Patients. | 0 |
| 36797240 | 2023 | Polo-like kinase 4 (Plk4) potentiates anoikis-resistance of p53KO mammary epithelial cells by inducing a hybrid EMT phenotype. | 0 |
| 36821942 | 2023 | Downregulation of Polo-like kinase 4 induces cell apoptosis and G2/M arrest in acute myeloid leukemia. | 0 |
| 36975767 | 2023 | NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β-dependent regulation of PLK4. | 3 |
| 37433832 | 2023 | Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells. | 0 |
| 37707473 | 2023 | Centrosomal organization of Cep152 provides flexibility in Plk4 and procentriole positioning. | 3 |
| 37773039 | 2023 | PLK4 self-phosphorylation drives the selection of a single site for procentriole assembly. | 1 |
| 35973104 | 2023 | Polo-like Kinase 4: the Variation During Therapy and its Relation to Treatment Response and Prognostic Risk Stratification in Childhood Acute Lymphoblastic Leukemia Patients. | 0 |
| 36797240 | 2023 | Polo-like kinase 4 (Plk4) potentiates anoikis-resistance of p53KO mammary epithelial cells by inducing a hybrid EMT phenotype. | 0 |
| 36821942 | 2023 | Downregulation of Polo-like kinase 4 induces cell apoptosis and G2/M arrest in acute myeloid leukemia. | 0 |
| 36975767 | 2023 | NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β-dependent regulation of PLK4. | 3 |
Citation
Dessen P
PLK4 (polo like kinase 4)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43733/plk4
