Identity
HGNC
LOCATION
Xq28
LOCUSID
ALIAS
CFF,HCF,HCF-1,HCF1,HFC1,MRX3,PPP1R89,VCAF
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3054
MIM: 300019
HGNC: 4839
Ensembl: ENSG00000172534
Variants:
dbSNP: 3054
ClinVar: 3054
TCGA: ENSG00000172534
COSMIC: HCFC1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000172534 | ENST00000310441 | P51610 |
| ENSG00000172534 | ENST00000369984 | A6NEM2 |
| ENSG00000172534 | ENST00000444191 | H7C1C4 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38956580 | 2024 | Variants in HCFC1 and MN1 genes causing intellectual disability in two Pakistani families. | 0 |
| 38956580 | 2024 | Variants in HCFC1 and MN1 genes causing intellectual disability in two Pakistani families. | 0 |
| 37264743 | 2023 | HCFC1 variants in the proteolysis domain are associated with X-linked idiopathic partial epilepsy: Exploring the underlying mechanism. | 3 |
| 37264743 | 2023 | HCFC1 variants in the proteolysis domain are associated with X-linked idiopathic partial epilepsy: Exploring the underlying mechanism. | 3 |
| 33517344 | 2021 | Novel exon-skipping variant disrupting the basic domain of HCFC1 causes intellectual disability without metabolic abnormalities in both male and female patients. | 6 |
| 33517344 | 2021 | Novel exon-skipping variant disrupting the basic domain of HCFC1 causes intellectual disability without metabolic abnormalities in both male and female patients. | 6 |
| 32479599 | 2020 | Host cell factors stimulate HIV-1 transcription by antagonizing substrate-binding function of Siah1 ubiquitin ligase to stabilize transcription elongation factor ELL2. | 11 |
| 33050986 | 2020 | MLL5, a histone modifying enzyme, regulates androgen receptor activity in prostate cancer cells by recruiting co-regulators, HCF1 and SET1. | 5 |
| 33097698 | 2020 | HCF-1 promotes cell cycle progression by regulating the expression of CDC42. | 2 |
| 32479599 | 2020 | Host cell factors stimulate HIV-1 transcription by antagonizing substrate-binding function of Siah1 ubiquitin ligase to stabilize transcription elongation factor ELL2. | 11 |
| 33050986 | 2020 | MLL5, a histone modifying enzyme, regulates androgen receptor activity in prostate cancer cells by recruiting co-regulators, HCF1 and SET1. | 5 |
| 33097698 | 2020 | HCF-1 promotes cell cycle progression by regulating the expression of CDC42. | 2 |
| 31227231 | 2019 | HCF-1 Regulates De Novo Lipogenesis through a Nutrient-Sensitive Complex with ChREBP. | 20 |
| 31693902 | 2019 | Heat-Shock Protein 90 Controls the Expression of Cell-Cycle Genes by Stabilizing Metazoan-Specific Host-Cell Factor HCFC1. | 11 |
| 31227231 | 2019 | HCF-1 Regulates De Novo Lipogenesis through a Nutrient-Sensitive Complex with ChREBP. | 20 |
Citation
Dessen P
HCFC1 (host cell factor C1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43736/hcfc1
