CDCA8 (cell division cycle associated 8)

2007-02-01  

Identity

HGNC
LOCATION
1p34.3
LOCUSID
ALIAS
BOR,BOREALIN,DasraB,MESRGP
FUSION GENES

Other Information

Locus ID:

NCBI: 55143
MIM: 609977
HGNC: 14629
Ensembl: ENSG00000134690

Variants:

dbSNP: 55143
ClinVar: 55143
TCGA: ENSG00000134690
COSMIC: CDCA8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134690ENST00000327331Q53HL2
ENSG00000134690ENST00000373055Q53HL2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
SUMOylationREACTOMER-HSA-2990846
SUMO E3 ligases SUMOylate target proteinsREACTOMER-HSA-3108232
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Resolution of Sister Chromatid CohesionREACTOMER-HSA-2500257
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Separation of Sister ChromatidsREACTOMER-HSA-2467813
SUMOylation of DNA replication proteinsREACTOMER-HSA-4615885

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
374283862024CDCA8 Facilitates Tumor Proliferation and Predicts a Poor Prognosis in Hepatocellular Carcinoma.2
374283862024CDCA8 Facilitates Tumor Proliferation and Predicts a Poor Prognosis in Hepatocellular Carcinoma.2
368558182023Cell division cycle-associated 8 is a prognostic biomarker related to immune invasion in hepatocellular carcinoma.3
368985122023A 1-kb human CDCA8 promoter directs the spermatogonia-specific luciferase expression in adult testis.0
378138762023CDCA8 promotes bladder cancer survival by stabilizing HIF1α expression under hypoxia.1
368558182023Cell division cycle-associated 8 is a prognostic biomarker related to immune invasion in hepatocellular carcinoma.3
368985122023A 1-kb human CDCA8 promoter directs the spermatogonia-specific luciferase expression in adult testis.0
378138762023CDCA8 promotes bladder cancer survival by stabilizing HIF1α expression under hypoxia.1
341177642022MiR-133a-3p inhibits the malignant progression of oesophageal cancer by targeting CDCA8.6
350940102022Methylation-dependent and -independent roles of EZH2 synergize in CDCA8 activation in prostate cancer.5
355759792022Regulators CDCA8 as potential targets and biomarkers for the prognosis of human skin cutaneous melanoma.2
341177642022MiR-133a-3p inhibits the malignant progression of oesophageal cancer by targeting CDCA8.6
350940102022Methylation-dependent and -independent roles of EZH2 synergize in CDCA8 activation in prostate cancer.5
355759792022Regulators CDCA8 as potential targets and biomarkers for the prognosis of human skin cutaneous melanoma.2
335422112021Double-targeting CDCA8 and E2F1 inhibits the growth and migration of malignant glioma.14

Citation

Dessen P

CDCA8 (cell division cycle associated 8)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43750/cdca8